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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TFRC
All Species:
19.7
Human Site:
S499
Identified Species:
39.39
UniProt:
P02786
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P02786
NP_001121620.1
760
84871
S499
S
N
F
K
V
S
A
S
P
L
L
Y
T
L
I
Chimpanzee
Pan troglodytes
XP_001137174
750
84310
P502
E
S
W
T
K
K
S
P
S
P
E
F
S
G
M
Rhesus Macaque
Macaca mulatta
XP_001101316
759
84759
S498
S
N
F
K
V
S
A
S
P
L
L
Y
T
L
I
Dog
Lupus familis
XP_546952
806
88711
S522
D
K
F
N
A
K
T
S
P
L
L
I
S
L
I
Cat
Felis silvestris
Mouse
Mus musculus
Q62351
763
85713
S502
S
N
F
K
V
S
A
S
P
L
L
Y
T
L
M
Rat
Rattus norvegicus
Q99376
622
70134
R386
I
D
G
K
Y
L
Y
R
N
S
N
W
I
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516658
498
55112
F262
Y
P
S
G
S
S
L
F
R
D
T
D
W
V
K
Chicken
Gallus gallus
Q90997
776
85640
S512
S
H
V
K
I
S
A
S
P
L
L
Y
M
L
L
Frog
Xenopus laevis
NP_001089576
754
85283
S496
D
S
G
F
E
G
K
S
L
Y
E
S
W
R
E
Zebra Danio
Brachydanio rerio
NP_001009917
770
84979
S498
D
S
F
K
A
A
A
S
P
L
L
Y
D
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P91406
770
85483
D508
R
G
R
K
T
L
Y
D
T
W
M
K
V
F
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M1S8
705
77149
V469
P
D
A
V
G
L
T
V
E
E
T
F
K
S
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.5
94.4
41.8
N.A.
76.9
61.9
N.A.
41.4
52.8
24
44.4
N.A.
N.A.
N.A.
20.6
N.A.
Protein Similarity:
100
42.3
96.9
57.9
N.A.
87.5
74
N.A.
51.4
69.7
43.2
64.9
N.A.
N.A.
N.A.
38.8
N.A.
P-Site Identity:
100
0
100
46.6
N.A.
93.3
6.6
N.A.
6.6
66.6
6.6
60
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
40
100
53.3
N.A.
100
20
N.A.
13.3
86.6
13.3
80
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
17
9
42
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
25
17
0
0
0
0
0
9
0
9
0
9
9
0
0
% D
% Glu:
9
0
0
0
9
0
0
0
9
9
17
0
0
0
9
% E
% Phe:
0
0
42
9
0
0
0
9
0
0
0
17
0
9
0
% F
% Gly:
0
9
17
9
9
9
0
0
0
0
0
0
0
9
0
% G
% His:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
0
9
0
0
0
0
0
0
9
9
0
25
% I
% Lys:
0
9
0
59
9
17
9
0
0
0
0
9
9
0
17
% K
% Leu:
0
0
0
0
0
25
9
0
9
50
50
0
0
50
17
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
0
9
0
17
% M
% Asn:
0
25
0
9
0
0
0
0
9
0
9
0
0
0
0
% N
% Pro:
9
9
0
0
0
0
0
9
50
9
0
0
0
0
9
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% Q
% Arg:
9
0
9
0
0
0
0
9
9
0
0
0
0
9
0
% R
% Ser:
34
25
9
0
9
42
9
59
9
9
0
9
17
17
0
% S
% Thr:
0
0
0
9
9
0
17
0
9
0
17
0
25
0
0
% T
% Val:
0
0
9
9
25
0
0
9
0
0
0
0
9
9
0
% V
% Trp:
0
0
9
0
0
0
0
0
0
9
0
9
17
0
0
% W
% Tyr:
9
0
0
0
9
0
17
0
0
9
0
42
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _