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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TFRC All Species: 16.06
Human Site: Y503 Identified Species: 32.12
UniProt: P02786 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P02786 NP_001121620.1 760 84871 Y503 V S A S P L L Y T L I E K T M
Chimpanzee Pan troglodytes XP_001137174 750 84310 F506 K K S P S P E F S G M P R I S
Rhesus Macaque Macaca mulatta XP_001101316 759 84759 Y502 V S A S P L L Y T L I E K T M
Dog Lupus familis XP_546952 806 88711 I526 A K T S P L L I S L I E N I L
Cat Felis silvestris
Mouse Mus musculus Q62351 763 85713 Y506 V S A S P L L Y T L M G K I M
Rat Rattus norvegicus Q99376 622 70134 W390 Y L Y R N S N W I S K I E E L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516658 498 55112 D266 S S L F R D T D W V K D V E P
Chicken Gallus gallus Q90997 776 85640 Y516 I S A S P L L Y M L L G S I M
Frog Xenopus laevis NP_001089576 754 85283 S500 E G K S L Y E S W R E K D P S
Zebra Danio Brachydanio rerio NP_001009917 770 84979 Y502 A A A S P L L Y D L L E S T M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P91406 770 85483 K512 T L Y D T W M K V F P D K K A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M1S8 705 77149 F473 G L T V E E T F K S Q N N I I
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 22.5 94.4 41.8 N.A. 76.9 61.9 N.A. 41.4 52.8 24 44.4 N.A. N.A. N.A. 20.6 N.A.
Protein Similarity: 100 42.3 96.9 57.9 N.A. 87.5 74 N.A. 51.4 69.7 43.2 64.9 N.A. N.A. N.A. 38.8 N.A.
P-Site Identity: 100 0 100 46.6 N.A. 80 0 N.A. 6.6 60 6.6 66.6 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 33.3 100 60 N.A. 86.6 20 N.A. 20 73.3 13.3 80 N.A. N.A. N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 22.1 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 40 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 9 42 0 0 0 0 0 0 0 0 0 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 9 0 9 0 9 9 0 0 17 9 0 0 % D
% Glu: 9 0 0 0 9 9 17 0 0 0 9 34 9 17 0 % E
% Phe: 0 0 0 9 0 0 0 17 0 9 0 0 0 0 0 % F
% Gly: 9 9 0 0 0 0 0 0 0 9 0 17 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 0 0 0 0 0 0 9 9 0 25 9 0 42 9 % I
% Lys: 9 17 9 0 0 0 0 9 9 0 17 9 34 9 0 % K
% Leu: 0 25 9 0 9 50 50 0 0 50 17 0 0 0 17 % L
% Met: 0 0 0 0 0 0 9 0 9 0 17 0 0 0 42 % M
% Asn: 0 0 0 0 9 0 9 0 0 0 0 9 17 0 0 % N
% Pro: 0 0 0 9 50 9 0 0 0 0 9 9 0 9 9 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % Q
% Arg: 0 0 0 9 9 0 0 0 0 9 0 0 9 0 0 % R
% Ser: 9 42 9 59 9 9 0 9 17 17 0 0 17 0 17 % S
% Thr: 9 0 17 0 9 0 17 0 25 0 0 0 0 25 0 % T
% Val: 25 0 0 9 0 0 0 0 9 9 0 0 9 0 0 % V
% Trp: 0 0 0 0 0 9 0 9 17 0 0 0 0 0 0 % W
% Tyr: 9 0 17 0 0 9 0 42 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _