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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HPX
All Species:
25.15
Human Site:
Y436
Identified Species:
61.48
UniProt:
P02790
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P02790
NP_000604.1
462
51676
Y436
H
G
P
N
L
Y
C
Y
S
D
V
E
K
L
N
Chimpanzee
Pan troglodytes
XP_508255
462
51671
Y436
H
G
P
N
L
Y
C
Y
S
D
V
E
K
L
N
Rhesus Macaque
Macaca mulatta
XP_001109797
462
51540
Y436
H
G
P
N
L
Y
C
Y
S
D
V
E
K
L
N
Dog
Lupus familis
XP_853676
458
51319
Y432
H
G
S
D
L
Y
C
Y
S
D
V
E
K
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q91X72
460
51322
Y434
H
G
P
N
L
Y
C
Y
S
S
I
D
K
L
N
Rat
Rattus norvegicus
P20059
460
51332
Y434
H
G
P
N
L
Y
C
Y
S
S
I
D
K
L
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516700
325
35480
G303
A
K
P
V
T
V
I
G
P
V
C
G
V
E
V
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080518
466
53339
D410
A
K
S
R
M
D
K
D
S
P
H
S
I
I
N
Zebra Danio
Brachydanio rerio
Q6PHG2
447
51008
Y420
I
G
N
H
F
Y
N
Y
D
S
V
Q
V
M
L
Tiger Blowfish
Takifugu rubipres
NP_001027761
442
49452
S417
S
K
Y
Y
Q
Y
A
S
V
T
I
L
A
L
S
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
94.1
80.7
N.A.
73.5
75.3
N.A.
23.3
N.A.
20.6
35.5
41.1
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
96.3
88
N.A.
82.9
83.7
N.A.
35.2
N.A.
37.9
53.6
56.9
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
80
N.A.
80
80
N.A.
6.6
N.A.
13.3
26.6
13.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
6.6
N.A.
26.6
46.6
26.6
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
60
0
0
0
10
0
0
0
0
% C
% Asp:
0
0
0
10
0
10
0
10
10
40
0
20
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
40
0
10
0
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
70
0
0
0
0
0
10
0
0
0
10
0
0
0
% G
% His:
60
0
0
10
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
10
0
0
0
30
0
10
10
0
% I
% Lys:
0
30
0
0
0
0
10
0
0
0
0
0
60
0
0
% K
% Leu:
0
0
0
0
60
0
0
0
0
0
0
10
0
70
10
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
10
50
0
0
10
0
0
0
0
0
0
0
60
% N
% Pro:
0
0
60
0
0
0
0
0
10
10
0
0
0
0
0
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
0
20
0
0
0
0
10
70
30
0
10
0
0
20
% S
% Thr:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% T
% Val:
0
0
0
10
0
10
0
0
10
10
50
0
20
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
10
0
80
0
70
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _