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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FTH1
All Species:
20.3
Human Site:
T175
Identified Species:
49.63
UniProt:
P02794
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P02794
NP_002023.2
183
21226
T175
E
Y
L
F
D
K
H
T
L
G
D
S
D
N
E
Chimpanzee
Pan troglodytes
XP_001140124
290
32457
T282
E
Y
L
F
D
K
H
T
L
G
D
S
D
N
E
Rhesus Macaque
Macaca mulatta
XP_001104405
183
21251
T175
E
Y
L
F
D
K
H
T
L
G
D
S
D
N
E
Dog
Lupus familis
XP_535550
183
21043
A175
E
Y
L
F
D
K
H
A
L
G
N
S
D
S
E
Cat
Felis silvestris
Mouse
Mus musculus
P09528
182
21048
T175
E
Y
L
F
D
K
H
T
L
G
H
G
D
E
S
Rat
Rattus norvegicus
P19132
182
21108
T175
E
Y
L
F
D
K
H
T
L
G
H
G
D
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514048
183
21245
T175
E
Y
L
F
D
K
H
T
L
G
D
S
D
N
E
Chicken
Gallus gallus
P08267
180
21073
H173
A
E
Y
L
F
D
K
H
T
L
G
E
S
D
S
Frog
Xenopus laevis
Q7SXA6
177
20900
H170
A
E
Y
L
F
D
K
H
T
L
G
E
D
H
E
Zebra Danio
Brachydanio rerio
NP_571660
177
20701
L170
A
E
Y
M
F
D
K
L
T
L
G
K
E
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63
98.9
76.5
N.A.
92.9
94.5
N.A.
92.9
90.7
79.2
75.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
63
99.4
85.7
N.A.
96.7
96.1
N.A.
97.8
94.5
92.9
87.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
80
N.A.
73.3
73.3
N.A.
100
0
13.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
73.3
73.3
N.A.
100
6.6
20
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
30
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
70
30
0
0
0
0
40
0
80
10
0
% D
% Glu:
70
30
0
0
0
0
0
0
0
0
0
20
10
20
60
% E
% Phe:
0
0
0
70
30
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
70
30
20
0
0
0
% G
% His:
0
0
0
0
0
0
70
20
0
0
20
0
0
10
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
70
30
0
0
0
0
10
0
0
0
% K
% Leu:
0
0
70
20
0
0
0
10
70
30
0
0
0
0
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
10
0
0
40
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
50
10
20
40
% S
% Thr:
0
0
0
0
0
0
0
60
30
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
70
30
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _