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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: F11 All Species: 10.3
Human Site: S286 Identified Species: 25.19
UniProt: P03951 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P03951 NP_000119.1 625 70109 S286 S L Q S C R H S I P V F C H S
Chimpanzee Pan troglodytes XP_001165847 625 70046 S286 S L Q S C R H S I P V F C H S
Rhesus Macaque Macaca mulatta XP_001090398 900 99753 C412 C D S M V Y G C D S M I Y E C
Dog Lupus familis XP_532838 629 70133 Y290 E P C H S K I Y S G V D F E G
Cat Felis silvestris
Mouse Mus musculus Q91Y47 624 69856 S286 S L Q H C R H S V P V F C H P
Rat Rattus norvegicus P14272 638 71255 A287 S L F T C R K A R P E P C H F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519233 360 39589 P22 Y L R T V F S P N V Q H C Q L
Chicken Gallus gallus XP_420678 663 75784 H322 G L L N C R R H F P A C N S R
Frog Xenopus laevis NP_001086768 629 69781 P291 K F S P S V C P L T M L S D S
Zebra Danio Brachydanio rerio XP_698179 533 59030 S195 Y R I S A E N S L L E I Q L E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 54.7 58.3 N.A. 77.5 57.2 N.A. 34 56.5 47.3 28.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.6 60.2 73.7 N.A. 86.7 72.5 N.A. 43.5 69.9 64.7 45.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 0 6.6 N.A. 80 46.6 N.A. 13.3 26.6 6.6 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 6.6 13.3 N.A. 86.6 60 N.A. 26.6 33.3 20 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 0 0 10 0 0 10 0 0 0 0 % A
% Cys: 10 0 10 0 50 0 10 10 0 0 0 10 50 0 10 % C
% Asp: 0 10 0 0 0 0 0 0 10 0 0 10 0 10 0 % D
% Glu: 10 0 0 0 0 10 0 0 0 0 20 0 0 20 10 % E
% Phe: 0 10 10 0 0 10 0 0 10 0 0 30 10 0 10 % F
% Gly: 10 0 0 0 0 0 10 0 0 10 0 0 0 0 10 % G
% His: 0 0 0 20 0 0 30 10 0 0 0 10 0 40 0 % H
% Ile: 0 0 10 0 0 0 10 0 20 0 0 20 0 0 0 % I
% Lys: 10 0 0 0 0 10 10 0 0 0 0 0 0 0 0 % K
% Leu: 0 60 10 0 0 0 0 0 20 10 0 10 0 10 10 % L
% Met: 0 0 0 10 0 0 0 0 0 0 20 0 0 0 0 % M
% Asn: 0 0 0 10 0 0 10 0 10 0 0 0 10 0 0 % N
% Pro: 0 10 0 10 0 0 0 20 0 50 0 10 0 0 10 % P
% Gln: 0 0 30 0 0 0 0 0 0 0 10 0 10 10 0 % Q
% Arg: 0 10 10 0 0 50 10 0 10 0 0 0 0 0 10 % R
% Ser: 40 0 20 30 20 0 10 40 10 10 0 0 10 10 30 % S
% Thr: 0 0 0 20 0 0 0 0 0 10 0 0 0 0 0 % T
% Val: 0 0 0 0 20 10 0 0 10 10 40 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 20 0 0 0 0 10 0 10 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _