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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
OPN1SW
All Species:
26.36
Human Site:
T335
Identified Species:
72.5
UniProt:
P03999
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P03999
NP_001699.1
348
39135
T335
D
T
C
S
S
Q
K
T
E
V
S
T
V
S
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001091869
349
39366
T336
D
I
S
S
S
Q
K
T
E
V
S
T
V
S
S
Dog
Lupus familis
XP_539386
348
39094
T335
E
M
S
S
S
Q
K
T
E
V
S
T
V
S
P
Cat
Felis silvestris
Mouse
Mus musculus
P51491
346
38903
T333
D
V
S
G
S
Q
K
T
E
V
S
T
V
S
S
Rat
Rattus norvegicus
Q63652
346
39043
T333
D
M
S
G
S
Q
K
T
E
V
S
T
V
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
NP_001121098
363
40227
T350
I
S
G
S
S
Q
A
T
Q
V
S
S
V
S
S
Chicken
Gallus gallus
P28684
347
38702
T334
A
S
T
S
A
Q
R
T
E
V
S
S
V
S
S
Frog
Xenopus laevis
P51473
347
38981
T334
V
S
S
T
S
Q
R
T
E
V
S
T
V
S
S
Zebra Danio
Brachydanio rerio
Q9W6A9
336
37250
E324
K
K
I
D
E
S
S
E
V
S
S
K
T
E
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96.2
88.5
N.A.
85
86.2
N.A.
51.7
79.8
75.8
60.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
97.1
92.8
N.A.
92.5
92.2
N.A.
69.6
89
88.2
73.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
86.6
73.3
N.A.
80
80
N.A.
60
60
66.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
86.6
80
N.A.
80
80
N.A.
80
86.6
86.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
12
0
12
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
45
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
12
0
0
0
12
0
0
12
78
0
0
0
0
12
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
12
23
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
12
12
12
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
12
12
0
0
0
0
56
0
0
0
0
12
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
23
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% P
% Gln:
0
0
0
0
0
89
0
0
12
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
23
0
0
0
0
0
0
0
0
% R
% Ser:
0
34
56
56
78
12
12
0
0
12
100
23
0
89
78
% S
% Thr:
0
12
12
12
0
0
0
89
0
0
0
67
12
0
12
% T
% Val:
12
12
0
0
0
0
0
0
12
89
0
0
89
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _