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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DNTT All Species: 31.82
Human Site: S282 Identified Species: 63.64
UniProt: P04053 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P04053 NP_001017520.1 509 58437 S282 S K V R S D K S L K F T R M Q
Chimpanzee Pan troglodytes XP_521569 509 58461 S282 S K V R S D K S L K F T R M Q
Rhesus Macaque Macaca mulatta XP_001100878 510 58547 S282 S K V R S D E S L K F T R M Q
Dog Lupus familis XP_849761 510 58444 S283 S K I K S D K S L K F T P M Q
Cat Felis silvestris
Mouse Mus musculus P09838 530 60313 S282 S K I Q S D K S L R F T Q M Q
Rat Rattus norvegicus NP_001012479 510 58470 S282 S K I K S D K S L R F T H M Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505901 514 59196 K279 L N E V I T D K T T L S T S L
Chicken Gallus gallus P36195 506 58429 T282 E E V K A D K T L K L S K M Q
Frog Xenopus laevis P42118 507 58827 E278 E E I K N E K E L K L T K M Q
Zebra Danio Brachydanio rerio NP_001014817 487 55201 S269 E Q V L T E P S I R L N R M Q
Tiger Blowfish Takifugu rubipres NP_001027915 498 56663 S271 D H I L A D Q S I Q L N H M Q
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796033 573 64326 I285 D D V K G S Y I L N L T R S Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 97.2 85.8 N.A. 77.9 82.5 N.A. 68.2 63.6 58.9 46.5 47.1 N.A. N.A. N.A. 36.1
Protein Similarity: 100 99.8 98.2 91.5 N.A. 85.2 89.6 N.A. 79.9 78.1 77.8 65.8 67.7 N.A. N.A. N.A. 52.1
P-Site Identity: 100 100 93.3 80 N.A. 73.3 73.3 N.A. 0 46.6 40 33.3 26.6 N.A. N.A. N.A. 33.3
P-Site Similarity: 100 100 100 93.3 N.A. 100 93.3 N.A. 6.6 86.6 80 66.6 60 N.A. N.A. N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 17 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 17 9 0 0 0 67 9 0 0 0 0 0 0 0 0 % D
% Glu: 25 17 9 0 0 17 9 9 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 50 0 0 0 0 % F
% Gly: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 9 0 0 0 0 0 0 0 0 0 0 17 0 0 % H
% Ile: 0 0 42 0 9 0 0 9 17 0 0 0 0 0 0 % I
% Lys: 0 50 0 42 0 0 59 9 0 50 0 0 17 0 0 % K
% Leu: 9 0 0 17 0 0 0 0 75 0 50 0 0 0 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 84 0 % M
% Asn: 0 9 0 0 9 0 0 0 0 9 0 17 0 0 0 % N
% Pro: 0 0 0 0 0 0 9 0 0 0 0 0 9 0 0 % P
% Gln: 0 9 0 9 0 0 9 0 0 9 0 0 9 0 92 % Q
% Arg: 0 0 0 25 0 0 0 0 0 25 0 0 42 0 0 % R
% Ser: 50 0 0 0 50 9 0 67 0 0 0 17 0 17 0 % S
% Thr: 0 0 0 0 9 9 0 9 9 9 0 67 9 0 0 % T
% Val: 0 0 50 9 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _