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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DNTT
All Species:
24.55
Human Site:
S350
Identified Species:
49.09
UniProt:
P04053
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P04053
NP_001017520.1
509
58437
S350
D
V
D
F
L
I
T
S
P
G
S
T
E
D
E
Chimpanzee
Pan troglodytes
XP_521569
509
58461
S350
D
V
D
F
L
I
T
S
P
G
S
T
E
D
E
Rhesus Macaque
Macaca mulatta
XP_001100878
510
58547
S350
D
V
D
F
L
I
T
S
P
G
S
T
E
D
E
Dog
Lupus familis
XP_849761
510
58444
S351
D
V
D
F
L
I
T
S
P
G
S
T
D
E
D
Cat
Felis silvestris
Mouse
Mus musculus
P09838
530
60313
S350
D
V
D
F
L
I
T
S
P
E
A
T
E
D
E
Rat
Rattus norvegicus
NP_001012479
510
58470
S350
D
V
D
F
L
I
T
S
P
E
A
T
E
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505901
514
59196
D350
D
V
D
F
L
I
S
D
P
E
S
G
Q
D
E
Chicken
Gallus gallus
P36195
506
58429
I348
G
H
D
I
D
F
L
I
T
S
P
G
Q
R
E
Frog
Xenopus laevis
P42118
507
58827
C346
D
V
D
I
L
I
T
C
A
R
K
G
K
E
K
Zebra Danio
Brachydanio rerio
NP_001014817
487
55201
A337
D
V
D
F
I
I
K
A
P
E
G
Q
E
D
R
Tiger Blowfish
Takifugu rubipres
NP_001027915
498
56663
T339
D
V
D
I
I
F
T
T
L
E
L
G
M
E
E
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796033
573
64326
H353
D
V
D
F
L
I
S
H
P
E
E
G
K
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.2
85.8
N.A.
77.9
82.5
N.A.
68.2
63.6
58.9
46.5
47.1
N.A.
N.A.
N.A.
36.1
Protein Similarity:
100
99.8
98.2
91.5
N.A.
85.2
89.6
N.A.
79.9
78.1
77.8
65.8
67.7
N.A.
N.A.
N.A.
52.1
P-Site Identity:
100
100
100
80
N.A.
86.6
80
N.A.
66.6
13.3
40
53.3
33.3
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
80
20
60
66.6
53.3
N.A.
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
9
9
0
17
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
92
0
100
0
9
0
0
9
0
0
0
0
9
50
9
% D
% Glu:
0
0
0
0
0
0
0
0
0
50
9
0
50
42
67
% E
% Phe:
0
0
0
75
0
17
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
0
0
0
0
0
0
34
9
42
0
0
0
% G
% His:
0
9
0
0
0
0
0
9
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
25
17
84
0
9
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
9
0
0
0
9
0
17
0
17
% K
% Leu:
0
0
0
0
75
0
9
0
9
0
9
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
75
0
9
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
9
17
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
9
0
0
0
9
9
% R
% Ser:
0
0
0
0
0
0
17
50
0
9
42
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
67
9
9
0
0
50
0
0
0
% T
% Val:
0
92
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _