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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GBA
All Species:
1.82
Human Site:
S16
Identified Species:
4
UniProt:
P04062
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P04062
NP_000148.2
536
59716
S16
E
E
C
P
K
P
L
S
R
V
S
I
M
A
G
Chimpanzee
Pan troglodytes
Q9BDT0
536
59646
G16
E
E
C
P
K
P
S
G
R
V
S
I
M
A
G
Rhesus Macaque
Macaca mulatta
XP_001106009
208
22459
Dog
Lupus familis
XP_855035
536
59574
G16
E
D
R
L
Q
P
L
G
R
V
S
I
M
A
A
Cat
Felis silvestris
Mouse
Mus musculus
P17439
515
57603
Y18
F
Q
A
V
S
W
A
Y
G
A
Q
P
C
I
P
Rat
Rattus norvegicus
NP_001121111
515
57473
Y18
F
Q
A
I
S
W
A
Y
G
A
Q
P
C
I
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_687471
518
58019
T16
L
L
A
G
I
I
T
T
A
R
A
D
S
K
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393207
522
59288
L17
K
I
M
W
K
A
V
L
L
I
A
I
L
S
A
Nematode Worm
Caenorhab. elegans
NP_500785
519
58229
Y16
L
L
I
F
L
A
F
Y
G
F
S
S
D
A
K
Sea Urchin
Strong. purpuratus
XP_787092
509
57762
A14
L
T
I
L
A
F
V
A
V
V
C
A
T
D
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7M4T0
480
51334
Conservation
Percent
Protein Identity:
100
99.4
36.9
90.4
N.A.
83.4
84.5
N.A.
N.A.
N.A.
N.A.
54.6
N.A.
N.A.
38.9
40.4
44.5
Protein Similarity:
100
99.4
37.3
93.8
N.A.
89.1
89.3
N.A.
N.A.
N.A.
N.A.
69.5
N.A.
N.A.
58.9
59.3
62.3
P-Site Identity:
100
86.6
0
60
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
0
N.A.
N.A.
13.3
13.3
6.6
P-Site Similarity:
100
86.6
0
73.3
N.A.
6.6
6.6
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
53.3
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
22.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
41.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
28
0
10
19
19
10
10
19
19
10
0
37
19
% A
% Cys:
0
0
19
0
0
0
0
0
0
0
10
0
19
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
0
0
0
10
10
10
10
% D
% Glu:
28
19
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
19
0
0
10
0
10
10
0
0
10
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
0
0
19
28
0
0
0
0
0
19
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
19
10
10
10
0
0
0
10
0
37
0
19
0
% I
% Lys:
10
0
0
0
28
0
0
0
0
0
0
0
0
10
10
% K
% Leu:
28
19
0
19
10
0
19
10
10
0
0
0
10
0
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
28
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
0
0
0
19
0
28
0
0
0
0
0
19
0
0
19
% P
% Gln:
0
19
0
0
10
0
0
0
0
0
19
0
0
0
0
% Q
% Arg:
0
0
10
0
0
0
0
0
28
10
0
0
0
0
0
% R
% Ser:
0
0
0
0
19
0
10
10
0
0
37
10
10
10
0
% S
% Thr:
0
10
0
0
0
0
10
10
0
0
0
0
10
0
0
% T
% Val:
0
0
0
10
0
0
19
0
10
37
0
0
0
0
0
% V
% Trp:
0
0
0
10
0
19
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
28
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _