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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GBA
All Species:
10.61
Human Site:
S220
Identified Species:
23.33
UniProt:
P04062
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P04062
NP_000148.2
536
59716
S220
L
L
A
S
P
W
T
S
P
T
W
L
K
T
N
Chimpanzee
Pan troglodytes
Q9BDT0
536
59646
S220
L
L
A
S
P
W
T
S
P
T
W
L
K
T
N
Rhesus Macaque
Macaca mulatta
XP_001106009
208
22459
Dog
Lupus familis
XP_855035
536
59574
S220
L
F
A
S
P
W
T
S
P
T
W
L
K
T
N
Cat
Felis silvestris
Mouse
Mus musculus
P17439
515
57603
S215
G
R
V
N
G
K
G
S
L
K
G
Q
P
G
D
Rat
Rattus norvegicus
NP_001121111
515
57473
S215
G
A
V
N
G
K
G
S
L
K
G
H
P
G
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_687471
518
58019
I213
L
K
T
N
G
A
L
I
G
K
G
S
L
K
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393207
522
59288
M217
A
W
S
A
P
T
W
M
K
T
N
H
K
I
N
Nematode Worm
Caenorhab. elegans
NP_500785
519
58229
V213
M
K
T
S
G
R
M
V
G
A
G
E
L
L
G
Sea Urchin
Strong. purpuratus
XP_787092
509
57762
N211
A
P
G
W
M
K
T
N
G
A
M
K
G
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7M4T0
480
51334
I182
W
M
K
L
N
R
A
I
Q
G
T
T
V
N
N
Conservation
Percent
Protein Identity:
100
99.4
36.9
90.4
N.A.
83.4
84.5
N.A.
N.A.
N.A.
N.A.
54.6
N.A.
N.A.
38.9
40.4
44.5
Protein Similarity:
100
99.4
37.3
93.8
N.A.
89.1
89.3
N.A.
N.A.
N.A.
N.A.
69.5
N.A.
N.A.
58.9
59.3
62.3
P-Site Identity:
100
100
0
93.3
N.A.
6.6
6.6
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
26.6
6.6
6.6
P-Site Similarity:
100
100
0
93.3
N.A.
20
20
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
40
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
22.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
41.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
10
28
10
0
10
10
0
0
19
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
19
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
19
0
10
0
37
0
19
0
28
10
37
0
10
28
28
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
19
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
19
0
0
0
0
0
10
0
% I
% Lys:
0
19
10
0
0
28
0
0
10
28
0
10
37
10
0
% K
% Leu:
37
19
0
10
0
0
10
0
19
0
0
28
19
10
0
% L
% Met:
10
10
0
0
10
0
10
10
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
28
10
0
0
10
0
0
10
0
0
10
46
% N
% Pro:
0
10
0
0
37
0
0
0
28
0
0
0
19
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% Q
% Arg:
0
10
0
0
0
19
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
10
37
0
0
0
46
0
0
0
10
0
0
0
% S
% Thr:
0
0
19
0
0
10
37
0
0
37
10
10
0
28
0
% T
% Val:
0
0
19
0
0
0
0
10
0
0
0
0
10
0
0
% V
% Trp:
10
10
0
10
0
28
10
0
0
0
28
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _