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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GBA
All Species:
23.64
Human Site:
S470
Identified Species:
52
UniProt:
P04062
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P04062
NP_000148.2
536
59716
S470
S
K
F
I
P
E
G
S
Q
R
V
G
L
V
A
Chimpanzee
Pan troglodytes
Q9BDT0
536
59646
S470
S
K
F
I
P
E
G
S
Q
R
V
G
L
V
A
Rhesus Macaque
Macaca mulatta
XP_001106009
208
22459
I144
S
Y
F
S
E
E
G
I
G
Y
N
I
I
R
V
Dog
Lupus familis
XP_855035
536
59574
S470
S
K
F
I
P
E
G
S
Q
R
V
G
L
A
A
Cat
Felis silvestris
Mouse
Mus musculus
P17439
515
57603
S449
S
K
F
I
P
E
G
S
Q
R
V
A
L
V
A
Rat
Rattus norvegicus
NP_001121111
515
57473
S449
S
K
F
I
P
E
G
S
Q
R
V
G
L
V
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_687471
518
58019
S452
S
K
F
L
W
E
E
S
Q
R
V
G
V
S
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393207
522
59288
S458
S
R
F
V
D
R
G
S
V
R
I
F
I
T
D
Nematode Worm
Caenorhab. elegans
NP_500785
519
58229
A451
S
K
F
V
K
P
G
A
I
R
V
G
I
N
I
Sea Urchin
Strong. purpuratus
XP_787092
509
57762
F445
M
Y
Y
H
L
G
H
F
S
K
F
I
A
P
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7M4T0
480
51334
W416
V
M
S
G
T
G
S
W
T
Y
G
D
G
S
G
Conservation
Percent
Protein Identity:
100
99.4
36.9
90.4
N.A.
83.4
84.5
N.A.
N.A.
N.A.
N.A.
54.6
N.A.
N.A.
38.9
40.4
44.5
Protein Similarity:
100
99.4
37.3
93.8
N.A.
89.1
89.3
N.A.
N.A.
N.A.
N.A.
69.5
N.A.
N.A.
58.9
59.3
62.3
P-Site Identity:
100
100
26.6
93.3
N.A.
93.3
100
N.A.
N.A.
N.A.
N.A.
60
N.A.
N.A.
33.3
46.6
0
P-Site Similarity:
100
100
33.3
93.3
N.A.
93.3
100
N.A.
N.A.
N.A.
N.A.
73.3
N.A.
N.A.
60
66.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
22.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
41.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
0
0
0
10
10
10
46
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
0
0
0
0
10
0
0
10
% D
% Glu:
0
0
0
0
10
64
10
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
82
0
0
0
0
10
0
0
10
10
0
0
10
% F
% Gly:
0
0
0
10
0
19
73
0
10
0
10
55
10
0
19
% G
% His:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
46
0
0
0
10
10
0
10
19
28
0
10
% I
% Lys:
0
64
0
0
10
0
0
0
0
10
0
0
0
0
0
% K
% Leu:
0
0
0
10
10
0
0
0
0
0
0
0
46
0
0
% L
% Met:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% N
% Pro:
0
0
0
0
46
10
0
0
0
0
0
0
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
55
0
0
0
0
0
0
% Q
% Arg:
0
10
0
0
0
10
0
0
0
73
0
0
0
10
0
% R
% Ser:
82
0
10
10
0
0
10
64
10
0
0
0
0
19
0
% S
% Thr:
0
0
0
0
10
0
0
0
10
0
0
0
0
10
0
% T
% Val:
10
0
0
19
0
0
0
0
10
0
64
0
10
37
10
% V
% Trp:
0
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
19
10
0
0
0
0
0
0
19
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _