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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GBA
All Species:
10
Human Site:
T75
Identified Species:
22
UniProt:
P04062
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P04062
NP_000148.2
536
59716
T75
P
T
F
P
A
L
G
T
F
S
R
Y
E
S
T
Chimpanzee
Pan troglodytes
Q9BDT0
536
59646
T75
P
T
F
P
A
L
G
T
F
S
R
Y
E
S
T
Rhesus Macaque
Macaca mulatta
XP_001106009
208
22459
Dog
Lupus familis
XP_855035
536
59574
T75
L
A
L
P
A
P
G
T
F
S
Q
Y
E
S
T
Cat
Felis silvestris
Mouse
Mus musculus
P17439
515
57603
A77
L
S
V
G
A
I
Q
A
N
R
T
G
T
G
L
Rat
Rattus norvegicus
NP_001121111
515
57473
A77
L
S
T
G
S
I
Q
A
N
R
T
G
T
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_687471
518
58019
G75
S
R
L
M
E
S
Q
G
Q
F
Q
K
N
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393207
522
59288
R76
F
H
W
Y
V
S
S
R
D
G
L
R
L
S
L
Nematode Worm
Caenorhab. elegans
NP_500785
519
58229
E75
G
K
R
M
N
R
S
E
L
K
H
T
T
S
S
Sea Urchin
Strong. purpuratus
XP_787092
509
57762
M73
F
R
L
D
K
E
E
M
P
I
R
N
R
P
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7M4T0
480
51334
T44
Y
S
A
P
V
R
G
T
G
T
P
G
S
N
S
Conservation
Percent
Protein Identity:
100
99.4
36.9
90.4
N.A.
83.4
84.5
N.A.
N.A.
N.A.
N.A.
54.6
N.A.
N.A.
38.9
40.4
44.5
Protein Similarity:
100
99.4
37.3
93.8
N.A.
89.1
89.3
N.A.
N.A.
N.A.
N.A.
69.5
N.A.
N.A.
58.9
59.3
62.3
P-Site Identity:
100
100
0
66.6
N.A.
6.6
0
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
6.6
6.6
13.3
P-Site Similarity:
100
100
0
73.3
N.A.
20
20
N.A.
N.A.
N.A.
N.A.
20
N.A.
N.A.
13.3
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
22.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
41.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
37
0
0
19
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
10
10
10
10
0
0
0
0
28
0
0
% E
% Phe:
19
0
19
0
0
0
0
0
28
10
0
0
0
0
0
% F
% Gly:
10
0
0
19
0
0
37
10
10
10
0
28
0
19
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
19
0
0
0
10
0
0
0
0
0
% I
% Lys:
0
10
0
0
10
0
0
0
0
10
0
10
0
0
0
% K
% Leu:
28
0
28
0
0
19
0
0
10
0
10
0
10
0
28
% L
% Met:
0
0
0
19
0
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
19
0
0
10
10
10
0
% N
% Pro:
19
0
0
37
0
10
0
0
10
0
10
0
0
10
0
% P
% Gln:
0
0
0
0
0
0
28
0
10
0
19
0
0
0
0
% Q
% Arg:
0
19
10
0
0
19
0
10
0
19
28
10
10
0
0
% R
% Ser:
10
28
0
0
10
19
19
0
0
28
0
0
10
55
19
% S
% Thr:
0
19
10
0
0
0
0
37
0
10
19
10
28
0
46
% T
% Val:
0
0
10
0
19
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
10
0
0
0
0
0
0
0
28
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _