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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GBA
All Species:
15.45
Human Site:
Y402
Identified Species:
34
UniProt:
P04062
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P04062
NP_000148.2
536
59716
Y402
S
W
D
R
G
M
Q
Y
S
H
S
I
I
T
N
Chimpanzee
Pan troglodytes
Q9BDT0
536
59646
Y402
S
W
D
R
G
M
Q
Y
S
H
S
I
I
T
N
Rhesus Macaque
Macaca mulatta
XP_001106009
208
22459
S82
S
G
R
R
M
E
L
S
T
G
T
I
Q
A
N
Dog
Lupus familis
XP_855035
536
59574
Y402
S
W
D
R
G
V
Q
Y
S
H
S
I
I
T
N
Cat
Felis silvestris
Mouse
Mus musculus
P17439
515
57603
T387
Q
Y
S
H
S
I
I
T
N
L
L
Y
H
V
T
Rat
Rattus norvegicus
NP_001121111
515
57473
T387
Q
Y
S
H
S
I
I
T
N
L
L
Y
H
V
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_687471
518
58019
H386
D
R
A
E
D
Y
A
H
D
I
I
Q
D
L
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393207
522
59288
Y390
S
W
E
R
G
K
R
Y
I
L
S
I
T
Q
Y
Nematode Worm
Caenorhab. elegans
NP_500785
519
58229
N385
S
R
A
E
Q
Y
A
N
D
L
I
K
D
M
G
Sea Urchin
Strong. purpuratus
XP_787092
509
57762
E383
L
G
S
W
E
R
G
E
S
Y
S
H
D
I
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7M4T0
480
51334
V354
A
S
G
V
T
A
W
V
L
G
T
D
T
N
D
Conservation
Percent
Protein Identity:
100
99.4
36.9
90.4
N.A.
83.4
84.5
N.A.
N.A.
N.A.
N.A.
54.6
N.A.
N.A.
38.9
40.4
44.5
Protein Similarity:
100
99.4
37.3
93.8
N.A.
89.1
89.3
N.A.
N.A.
N.A.
N.A.
69.5
N.A.
N.A.
58.9
59.3
62.3
P-Site Identity:
100
100
26.6
93.3
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
46.6
6.6
13.3
P-Site Similarity:
100
100
40
100
N.A.
20
20
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
60
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
22.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
41.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
19
0
0
10
19
0
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
28
0
10
0
0
0
19
0
0
10
28
0
10
% D
% Glu:
0
0
10
19
10
10
0
10
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
19
10
0
37
0
10
0
0
19
0
0
0
0
10
% G
% His:
0
0
0
19
0
0
0
10
0
28
0
10
19
0
0
% H
% Ile:
0
0
0
0
0
19
19
0
10
10
19
46
28
10
10
% I
% Lys:
0
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% K
% Leu:
10
0
0
0
0
0
10
0
10
37
19
0
0
10
0
% L
% Met:
0
0
0
0
10
19
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
10
19
0
0
0
0
10
46
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
19
0
0
0
10
0
28
0
0
0
0
10
10
10
0
% Q
% Arg:
0
19
10
46
0
10
10
0
0
0
0
0
0
0
0
% R
% Ser:
55
10
28
0
19
0
0
10
37
0
46
0
0
0
0
% S
% Thr:
0
0
0
0
10
0
0
19
10
0
19
0
19
28
19
% T
% Val:
0
0
0
10
0
10
0
10
0
0
0
0
0
19
0
% V
% Trp:
0
37
0
10
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
19
0
0
0
19
0
37
0
10
0
19
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _