Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PROC All Species: 1.52
Human Site: S25 Identified Species: 3.7
UniProt: P04070 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P04070 NP_000303.1 461 52071 S25 G T P A P L D S V F S S S E R
Chimpanzee Pan troglodytes Q2F9P2 466 51600 R43 X W K P G P H R V F I T Q E E
Rhesus Macaque Macaca mulatta Q28506 161 17752
Dog Lupus familis XP_534191 486 53473 S33 L S P E R A S S V L G R V R R
Cat Felis silvestris
Mouse Mus musculus P33587 460 51800 P25 S I P A H P D P V F S S S E H
Rat Rattus norvegicus P31394 461 51893 P25 G V S A H P D P V F S S S E G
Wallaby Macropus eugenll
Platypus Ornith. anatinus NP_001121086 469 52177 K33 I N Q E D A N K V L G R A K R
Chicken Gallus gallus P25155 475 53123 K33 I K K E S A D K F L E R T K R
Frog Xenopus laevis NP_001080424 455 51792 P31 S P N A E S S P V F S S R Q E
Zebra Danio Brachydanio rerio NP_956650 434 48498 F25 G A L C K S V F S S S S N A H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 40.1 33.4 35.3 N.A. 68.7 68.5 N.A. 38.1 37.4 50.9 45.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 56.8 34.2 52.4 N.A. 81.5 81.5 N.A. 58 56.6 65.9 61.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 20 0 26.6 N.A. 60 60 N.A. 13.3 13.3 33.3 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 26.6 0 33.3 N.A. 60 60 N.A. 33.3 26.6 40 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 40 0 30 0 0 0 0 0 0 10 10 0 % A
% Cys: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 10 0 40 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 30 10 0 0 0 0 0 10 0 0 40 20 % E
% Phe: 0 0 0 0 0 0 0 10 10 50 0 0 0 0 0 % F
% Gly: 30 0 0 0 10 0 0 0 0 0 20 0 0 0 10 % G
% His: 0 0 0 0 20 0 10 0 0 0 0 0 0 0 20 % H
% Ile: 20 10 0 0 0 0 0 0 0 0 10 0 0 0 0 % I
% Lys: 0 10 20 0 10 0 0 20 0 0 0 0 0 20 0 % K
% Leu: 10 0 10 0 0 10 0 0 0 30 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 10 0 0 0 10 0 0 0 0 0 10 0 0 % N
% Pro: 0 10 30 10 10 30 0 30 0 0 0 0 0 0 0 % P
% Gln: 0 0 10 0 0 0 0 0 0 0 0 0 10 10 0 % Q
% Arg: 0 0 0 0 10 0 0 10 0 0 0 30 10 10 40 % R
% Ser: 20 10 10 0 10 20 20 20 10 10 50 50 30 0 0 % S
% Thr: 0 10 0 0 0 0 0 0 0 0 0 10 10 0 0 % T
% Val: 0 10 0 0 0 0 10 0 70 0 0 0 10 0 0 % V
% Trp: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _