KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PROC
All Species:
1.52
Human Site:
S25
Identified Species:
3.7
UniProt:
P04070
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P04070
NP_000303.1
461
52071
S25
G
T
P
A
P
L
D
S
V
F
S
S
S
E
R
Chimpanzee
Pan troglodytes
Q2F9P2
466
51600
R43
X
W
K
P
G
P
H
R
V
F
I
T
Q
E
E
Rhesus Macaque
Macaca mulatta
Q28506
161
17752
Dog
Lupus familis
XP_534191
486
53473
S33
L
S
P
E
R
A
S
S
V
L
G
R
V
R
R
Cat
Felis silvestris
Mouse
Mus musculus
P33587
460
51800
P25
S
I
P
A
H
P
D
P
V
F
S
S
S
E
H
Rat
Rattus norvegicus
P31394
461
51893
P25
G
V
S
A
H
P
D
P
V
F
S
S
S
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
NP_001121086
469
52177
K33
I
N
Q
E
D
A
N
K
V
L
G
R
A
K
R
Chicken
Gallus gallus
P25155
475
53123
K33
I
K
K
E
S
A
D
K
F
L
E
R
T
K
R
Frog
Xenopus laevis
NP_001080424
455
51792
P31
S
P
N
A
E
S
S
P
V
F
S
S
R
Q
E
Zebra Danio
Brachydanio rerio
NP_956650
434
48498
F25
G
A
L
C
K
S
V
F
S
S
S
S
N
A
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.1
33.4
35.3
N.A.
68.7
68.5
N.A.
38.1
37.4
50.9
45.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
56.8
34.2
52.4
N.A.
81.5
81.5
N.A.
58
56.6
65.9
61.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
20
0
26.6
N.A.
60
60
N.A.
13.3
13.3
33.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
0
33.3
N.A.
60
60
N.A.
33.3
26.6
40
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
40
0
30
0
0
0
0
0
0
10
10
0
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
40
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
30
10
0
0
0
0
0
10
0
0
40
20
% E
% Phe:
0
0
0
0
0
0
0
10
10
50
0
0
0
0
0
% F
% Gly:
30
0
0
0
10
0
0
0
0
0
20
0
0
0
10
% G
% His:
0
0
0
0
20
0
10
0
0
0
0
0
0
0
20
% H
% Ile:
20
10
0
0
0
0
0
0
0
0
10
0
0
0
0
% I
% Lys:
0
10
20
0
10
0
0
20
0
0
0
0
0
20
0
% K
% Leu:
10
0
10
0
0
10
0
0
0
30
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
10
0
0
0
10
0
0
0
0
0
10
0
0
% N
% Pro:
0
10
30
10
10
30
0
30
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
0
0
0
0
0
0
0
0
0
10
10
0
% Q
% Arg:
0
0
0
0
10
0
0
10
0
0
0
30
10
10
40
% R
% Ser:
20
10
10
0
10
20
20
20
10
10
50
50
30
0
0
% S
% Thr:
0
10
0
0
0
0
0
0
0
0
0
10
10
0
0
% T
% Val:
0
10
0
0
0
0
10
0
70
0
0
0
10
0
0
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _