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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PROC
All Species:
13.33
Human Site:
Y268
Identified Species:
32.59
UniProt:
P04070
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P04070
NP_000303.1
461
52071
Y268
L
L
V
R
L
G
E
Y
D
L
R
R
W
E
K
Chimpanzee
Pan troglodytes
Q2F9P2
466
51600
G269
R
N
L
I
A
V
L
G
E
H
D
L
S
E
H
Rhesus Macaque
Macaca mulatta
Q28506
161
17752
Dog
Lupus familis
XP_534191
486
53473
R296
F
T
V
R
V
G
E
R
D
T
D
K
E
E
G
Cat
Felis silvestris
Mouse
Mus musculus
P33587
460
51800
Y268
L
T
V
R
L
G
E
Y
D
L
R
R
R
D
H
Rat
Rattus norvegicus
P31394
461
51893
Y269
L
T
V
R
L
G
E
Y
D
L
R
R
R
D
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
NP_001121086
469
52177
R288
F
K
V
R
V
G
E
R
D
T
E
K
K
D
S
Chicken
Gallus gallus
P25155
475
53123
V297
I
K
V
V
V
G
E
V
D
R
E
K
E
E
H
Frog
Xenopus laevis
NP_001080424
455
51792
Y251
Y
S
V
R
L
G
E
Y
D
I
R
K
L
E
D
Zebra Danio
Brachydanio rerio
NP_956650
434
48498
Y251
F
S
V
R
L
G
D
Y
Q
R
F
K
F
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.1
33.4
35.3
N.A.
68.7
68.5
N.A.
38.1
37.4
50.9
45.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
56.8
34.2
52.4
N.A.
81.5
81.5
N.A.
58
56.6
65.9
61.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
0
40
N.A.
73.3
73.3
N.A.
33.3
33.3
60
40
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
0
53.3
N.A.
80
80
N.A.
53.3
53.3
73.3
60
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
70
0
20
0
0
30
10
% D
% Glu:
0
0
0
0
0
0
70
0
10
0
20
0
20
60
0
% E
% Phe:
30
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% F
% Gly:
0
0
0
0
0
80
0
10
0
0
0
0
0
0
20
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
30
% H
% Ile:
10
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
0
20
0
0
0
0
0
0
0
0
0
50
10
0
10
% K
% Leu:
30
10
10
0
50
0
10
0
0
30
0
10
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Q
% Arg:
10
0
0
70
0
0
0
20
0
20
40
30
20
0
0
% R
% Ser:
0
20
0
0
0
0
0
0
0
0
0
0
10
0
10
% S
% Thr:
0
30
0
0
0
0
0
0
0
20
0
0
0
0
0
% T
% Val:
0
0
80
10
30
10
0
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
10
0
0
0
0
0
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _