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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ANXA1 All Species: 33.64
Human Site: T216 Identified Species: 82.22
UniProt: P04083 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P04083 NP_000691.1 346 38714 T216 A G E R R K G T D V N V F N T
Chimpanzee Pan troglodytes A5A6M2 346 38724 T216 A G E R R K G T D V N V F N T
Rhesus Macaque Macaca mulatta XP_001098092 346 38707 T216 A G E R R K G T D V N V F N T
Dog Lupus familis XP_533524 345 38608 T216 A G E R R K G T D V N V F I T
Cat Felis silvestris
Mouse Mus musculus P10107 346 38716 T216 A G E R R K G T D V N V F T T
Rat Rattus norvegicus P07150 346 38811 T216 A G E R R K G T D V N V F N T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506169 346 38399 T216 A G E K R K G T D V N V F N T
Chicken Gallus gallus P17785 339 38622 P211 K R K G T D V P K W I N I M T
Frog Xenopus laevis P27006 340 38527 T209 A G V K R K G T D V G K W I T
Zebra Danio Brachydanio rerio NP_861423 340 37736 T211 A G E K R K G T D C S V F I D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 99.1 91.3 N.A. 87.5 89 N.A. 83.5 51.7 50.2 65 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 100 99.1 95.6 N.A. 93.3 93.9 N.A. 90.4 68.5 66.7 74.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 93.3 N.A. 93.3 100 N.A. 93.3 6.6 60 66.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 100 N.A. 100 13.3 73.3 80 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 90 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 10 0 0 90 0 0 0 0 0 10 % D
% Glu: 0 0 80 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 80 0 0 % F
% Gly: 0 90 0 10 0 0 90 0 0 0 10 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 10 0 10 30 0 % I
% Lys: 10 0 10 30 0 90 0 0 10 0 0 10 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 70 10 0 50 0 % N
% Pro: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 10 0 60 90 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % S
% Thr: 0 0 0 0 10 0 0 90 0 0 0 0 0 10 90 % T
% Val: 0 0 10 0 0 0 10 0 0 80 0 80 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 10 0 0 10 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _