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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANXA1
All Species:
26.67
Human Site:
Y21
Identified Species:
65.19
UniProt:
P04083
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P04083
NP_000691.1
346
38714
Y21
I
E
N
E
E
Q
E
Y
V
Q
T
V
K
S
S
Chimpanzee
Pan troglodytes
A5A6M2
346
38724
Y21
I
E
N
E
E
Q
E
Y
V
Q
T
V
K
S
S
Rhesus Macaque
Macaca mulatta
XP_001098092
346
38707
Y21
I
E
N
E
E
Q
E
Y
V
Q
T
V
K
S
S
Dog
Lupus familis
XP_533524
345
38608
Y21
I
E
N
E
E
Q
E
Y
I
E
T
V
K
G
S
Cat
Felis silvestris
Mouse
Mus musculus
P10107
346
38716
Y21
L
E
N
Q
E
Q
E
Y
V
Q
A
V
K
S
Y
Rat
Rattus norvegicus
P07150
346
38811
Y21
I
E
K
Q
E
Q
E
Y
V
Q
A
V
K
S
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506169
346
38399
Y21
M
D
N
E
E
Q
E
Y
I
K
T
T
K
G
S
Chicken
Gallus gallus
P17785
339
38622
P20
L
E
G
D
H
S
L
P
P
S
A
Y
A
T
V
Frog
Xenopus laevis
P27006
340
38527
A20
L
E
G
N
Q
S
C
A
R
Q
S
A
L
G
T
Zebra Danio
Brachydanio rerio
NP_861423
340
37736
T20
Y
Q
G
M
Q
E
T
T
V
Q
D
I
T
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.1
91.3
N.A.
87.5
89
N.A.
83.5
51.7
50.2
65
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
99.1
95.6
N.A.
93.3
93.9
N.A.
90.4
68.5
66.7
74.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
80
N.A.
73.3
73.3
N.A.
60
6.6
13.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
80
N.A.
86.6
26.6
40
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
0
0
30
10
10
0
0
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
10
0
0
0
0
0
0
10
0
0
0
0
% D
% Glu:
0
80
0
50
70
10
70
0
0
10
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
30
0
0
0
0
0
0
0
0
0
0
30
0
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
50
0
0
0
0
0
0
0
20
0
0
10
0
0
0
% I
% Lys:
0
0
10
0
0
0
0
0
0
10
0
0
70
0
0
% K
% Leu:
30
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% L
% Met:
10
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
60
10
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% P
% Gln:
0
10
0
20
20
70
0
0
0
70
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
20
0
0
0
10
10
0
0
50
50
% S
% Thr:
0
0
0
0
0
0
10
10
0
0
50
10
10
10
10
% T
% Val:
0
0
0
0
0
0
0
0
60
0
0
60
0
0
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
70
0
0
0
10
0
0
20
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _