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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDGFA
All Species:
25.76
Human Site:
S143
Identified Species:
70.83
UniProt:
P04085
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P04085
NP_002598.4
211
24043
S143
S
S
V
K
C
Q
P
S
R
V
H
H
R
S
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001096150
199
22477
S139
C
T
G
C
C
N
T
S
S
V
K
C
Q
P
S
Dog
Lupus familis
XP_848598
473
51017
S405
S
S
V
K
C
Q
P
S
R
I
H
H
R
S
V
Cat
Felis silvestris
Mouse
Mus musculus
P20033
211
24083
S143
S
S
V
K
C
Q
P
S
R
V
H
H
R
S
V
Rat
Rattus norvegicus
P28576
204
23288
S143
S
S
V
K
C
Q
P
S
R
V
H
H
R
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511880
289
32728
S221
S
S
V
K
C
Q
P
S
R
I
H
H
R
S
V
Chicken
Gallus gallus
NP_989637
194
22344
S136
C
T
G
C
C
N
T
S
S
V
K
C
Q
P
S
Frog
Xenopus laevis
P13698
226
25701
S148
S
S
V
K
C
Q
P
S
R
I
H
H
R
S
V
Zebra Danio
Brachydanio rerio
O73682
188
21738
K130
T
K
C
E
C
R
P
K
A
E
V
K
A
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
81
40.3
N.A.
92.4
88.6
N.A.
59.5
72.9
71.2
20.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
83.8
42.7
N.A.
96.6
93.8
N.A.
66.4
82.9
80
37.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
20
93.3
N.A.
100
100
N.A.
93.3
20
93.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
33.3
100
N.A.
100
100
N.A.
100
33.3
100
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
12
0
0
0
12
0
0
% A
% Cys:
23
0
12
23
100
0
0
0
0
0
0
23
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
12
0
0
0
0
0
12
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
23
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
67
67
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
34
0
0
0
0
0
% I
% Lys:
0
12
0
67
0
0
0
12
0
0
23
12
0
12
12
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
23
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
78
0
0
0
0
0
0
23
0
% P
% Gln:
0
0
0
0
0
67
0
0
0
0
0
0
23
0
0
% Q
% Arg:
0
0
0
0
0
12
0
0
67
0
0
0
67
0
0
% R
% Ser:
67
67
0
0
0
0
0
89
23
0
0
0
0
67
23
% S
% Thr:
12
23
0
0
0
0
23
0
0
0
0
0
0
0
0
% T
% Val:
0
0
67
0
0
0
0
0
0
56
12
0
0
0
67
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _