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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDGFA
All Species:
4.85
Human Site:
Y188
Identified Species:
13.33
UniProt:
P04085
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P04085
NP_002598.4
211
24043
Y188
T
T
S
L
N
P
D
Y
R
E
E
D
T
G
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001096150
199
22477
H177
V
Q
V
R
L
E
E
H
L
E
C
A
C
A
T
Dog
Lupus familis
XP_848598
473
51017
H450
T
S
G
L
N
P
D
H
R
E
E
E
T
G
R
Cat
Felis silvestris
Mouse
Mus musculus
P20033
211
24083
H188
T
S
N
L
N
P
D
H
R
E
E
E
T
G
R
Rat
Rattus norvegicus
P28576
204
23288
S182
L
E
C
A
C
A
T
S
N
L
N
P
D
H
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511880
289
32728
Y266
S
L
N
S
N
S
D
Y
R
E
E
E
T
G
R
Chicken
Gallus gallus
NP_989637
194
22344
E172
K
E
V
L
V
R
L
E
E
H
M
E
C
T
C
Frog
Xenopus laevis
P13698
226
25701
P203
E
T
G
F
F
T
S
P
A
L
V
L
T
G
R
Zebra Danio
Brachydanio rerio
O73682
188
21738
T166
C
K
C
S
C
K
F
T
Q
M
Q
C
K
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
81
40.3
N.A.
92.4
88.6
N.A.
59.5
72.9
71.2
20.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
83.8
42.7
N.A.
96.6
93.8
N.A.
66.4
82.9
80
37.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
6.6
73.3
N.A.
73.3
6.6
N.A.
60
6.6
26.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
20
93.3
N.A.
100
6.6
N.A.
80
13.3
26.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
0
12
0
0
12
0
0
12
0
12
0
% A
% Cys:
12
0
23
0
23
0
0
0
0
0
12
12
23
0
12
% C
% Asp:
0
0
0
0
0
0
45
0
0
0
0
12
12
0
0
% D
% Glu:
12
23
0
0
0
12
12
12
12
56
45
45
0
0
0
% E
% Phe:
0
0
0
12
12
0
12
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
23
0
0
0
0
0
0
0
0
0
0
56
0
% G
% His:
0
0
0
0
0
0
0
34
0
12
0
0
0
12
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
12
12
0
0
0
12
0
0
0
0
0
0
12
0
0
% K
% Leu:
12
12
0
45
12
0
12
0
12
23
0
12
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
12
12
0
0
0
0
% M
% Asn:
0
0
23
0
45
0
0
0
12
0
12
0
0
0
0
% N
% Pro:
0
0
0
0
0
34
0
12
0
0
0
12
0
0
0
% P
% Gln:
0
12
0
0
0
0
0
0
12
0
12
0
0
0
0
% Q
% Arg:
0
0
0
12
0
12
0
0
45
0
0
0
0
0
78
% R
% Ser:
12
23
12
23
0
12
12
12
0
0
0
0
0
12
0
% S
% Thr:
34
23
0
0
0
12
12
12
0
0
0
0
56
12
12
% T
% Val:
12
0
23
0
12
0
0
0
0
0
12
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
23
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _