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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RLN2
All Species:
5.45
Human Site:
S53
Identified Species:
13.33
UniProt:
P04090
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P04090
NP_005050.2
185
21043
S53
I
C
G
M
S
T
W
S
K
R
S
L
S
Q
E
Chimpanzee
Pan troglodytes
P51455
166
18742
S34
I
C
G
K
S
T
W
S
K
R
S
L
S
Q
E
Rhesus Macaque
Macaca mulatta
P19884
185
20877
G53
I
C
G
K
S
T
L
G
K
R
S
L
N
Q
E
Dog
Lupus familis
XP_853484
139
15013
V12
P
L
L
L
L
L
A
V
W
V
L
A
G
E
L
Cat
Felis silvestris
Mouse
Mus musculus
P47932
185
20552
G53
K
I
C
G
A
S
V
G
R
L
A
L
S
Q
E
Rat
Rattus norvegicus
P01347
186
20471
R54
V
C
G
A
S
V
G
R
L
A
L
S
Q
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
NP_001116159
180
20648
T47
F
I
R
T
V
I
F
T
C
G
G
S
R
W
R
Chicken
Gallus gallus
NP_001106671
192
20412
K61
T
C
G
G
S
R
W
K
R
L
S
L
M
A
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038445
151
16006
S24
K
A
L
D
A
G
P
S
Y
G
V
K
L
C
G
Tiger Blowfish
Takifugu rubipres
NP_001092112
128
14356
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.1
82.6
24.8
N.A.
48.6
48.3
N.A.
31.3
22.9
N.A.
27.5
24.3
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
89.1
89.7
40.5
N.A.
63.7
63.4
N.A.
47.5
38.5
N.A.
43.7
38.3
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
73.3
0
N.A.
26.6
26.6
N.A.
0
40
N.A.
6.6
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
80
13.3
N.A.
53.3
40
N.A.
13.3
46.6
N.A.
13.3
0
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
20
0
10
0
0
10
10
10
0
10
0
% A
% Cys:
0
50
10
0
0
0
0
0
10
0
0
0
0
10
0
% C
% Asp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
20
50
% E
% Phe:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
50
20
0
10
10
20
0
20
10
0
10
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
30
20
0
0
0
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
20
0
0
20
0
0
0
10
30
0
0
10
0
0
0
% K
% Leu:
0
10
20
10
10
10
10
0
10
20
20
50
10
0
10
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
10
0
10
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% N
% Pro:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
10
40
0
% Q
% Arg:
0
0
10
0
0
10
0
10
20
30
0
0
10
0
10
% R
% Ser:
0
0
0
0
50
10
0
30
0
0
40
20
30
0
0
% S
% Thr:
10
0
0
10
0
30
0
10
0
0
0
0
0
0
0
% T
% Val:
10
0
0
0
10
10
10
10
0
10
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
30
0
10
0
0
0
0
10
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _