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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: APOB All Species: 23.03
Human Site: S4438 Identified Species: 63.33
UniProt: P04114 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P04114 NP_000375.2 4563 515563 S4438 N F T S Q L S S Q V E Q F L H
Chimpanzee Pan troglodytes XP_515323 4562 515571 S4437 D F T S Q L S S Q V E Q F L H
Rhesus Macaque Macaca mulatta XP_001097500 4555 515274 S4430 D F T S Q L S S Q V E Q F L H
Dog Lupus familis XP_532887 4500 509109 S4373 D L V S Q L S S K V E Q F V Q
Cat Felis silvestris
Mouse Mus musculus NP_033823 4505 509414 T4378 D F A S K M S T Q V E Q F V S
Rat Rattus norvegicus Q7TMA5 4743 536006 T4346 D F A S K M S T Q V E Q F V S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511145 4612 517181 E4432 D L T S K L V E Q V N E F I S
Chicken Gallus gallus NP_001038098 4631 523347 D4433 D L V T R L T D Q V R E L V E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_694827 4418 495968 T4294 D F L N S L K T E K L E E I S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.3 94.1 74.1 N.A. 69.6 64.2 N.A. 59.1 49.7 N.A. 34.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.1 97 84.5 N.A. 81.9 77.2 N.A. 76.5 69.9 N.A. 56.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 93.3 93.3 60 N.A. 53.3 53.3 N.A. 40 20 N.A. 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 80 N.A. 86.6 86.6 N.A. 66.6 60 N.A. 53.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 23 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 89 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 12 12 0 67 34 12 0 12 % E
% Phe: 0 67 0 0 0 0 0 0 0 0 0 0 78 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 34 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 23 0 % I
% Lys: 0 0 0 0 34 0 12 0 12 12 0 0 0 0 0 % K
% Leu: 0 34 12 0 0 78 0 0 0 0 12 0 12 34 0 % L
% Met: 0 0 0 0 0 23 0 0 0 0 0 0 0 0 0 % M
% Asn: 12 0 0 12 0 0 0 0 0 0 12 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 45 0 0 0 78 0 0 67 0 0 12 % Q
% Arg: 0 0 0 0 12 0 0 0 0 0 12 0 0 0 0 % R
% Ser: 0 0 0 78 12 0 67 45 0 0 0 0 0 0 45 % S
% Thr: 0 0 45 12 0 0 12 34 0 0 0 0 0 0 0 % T
% Val: 0 0 23 0 0 0 12 0 0 89 0 0 0 45 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _