KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SOD2
All Species:
48.79
Human Site:
S127
Identified Species:
67.08
UniProt:
P04179
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P04179
NP_000627.2
222
24722
S127
A
I
K
R
D
F
G
S
F
D
K
F
K
E
K
Chimpanzee
Pan troglodytes
Q8HXP7
198
22186
A114
F
K
E
K
L
T
A
A
S
V
G
V
Q
G
S
Rhesus Macaque
Macaca mulatta
Q8HXP2
198
22191
A114
F
K
E
K
L
T
A
A
S
V
G
V
Q
G
S
Dog
Lupus familis
XP_862558
183
20786
G102
K
L
T
T
V
S
V
G
V
Q
G
S
G
W
G
Cat
Felis silvestris
Mouse
Mus musculus
P09671
222
24584
S127
A
I
K
R
D
F
G
S
F
E
K
F
K
E
K
Rat
Rattus norvegicus
P07895
222
24656
S127
A
I
K
R
D
F
G
S
F
E
K
F
K
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519389
312
34579
S217
A
I
K
R
D
F
G
S
F
E
K
F
K
E
K
Chicken
Gallus gallus
NP_989542
224
24928
S129
A
I
K
R
D
F
G
S
F
A
N
F
K
E
K
Frog
Xenopus laevis
NP_001083968
224
25147
S129
A
I
K
R
D
F
G
S
F
E
K
F
K
E
K
Zebra Danio
Brachydanio rerio
NP_956270
224
24990
S129
A
I
K
R
D
F
G
S
F
Q
K
M
K
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q00637
217
24666
S119
A
I
E
S
Q
W
K
S
L
E
E
F
K
K
E
Honey Bee
Apis mellifera
NP_001171519
218
24507
S122
Q
I
K
K
D
F
G
S
I
E
E
M
K
K
R
Nematode Worm
Caenorhab. elegans
P31161
221
24518
S126
A
I
K
S
D
F
G
S
L
D
N
L
Q
K
Q
Sea Urchin
Strong. purpuratus
XP_785278
224
24586
S128
V
I
K
K
D
F
G
S
Y
D
D
M
R
S
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P09233
235
25527
S139
A
I
D
E
D
F
G
S
F
E
A
L
V
K
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O81235
231
25425
S135
A
I
D
A
H
F
G
S
L
E
G
L
V
K
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q9Y783
245
27001
S140
E
I
E
K
T
W
G
S
F
D
E
F
K
K
A
Conservation
Percent
Protein Identity:
100
89.1
88.2
76.1
N.A.
89.6
88.2
N.A.
63.1
83.9
81.2
80.3
N.A.
58.5
62.6
64.4
61.1
Protein Similarity:
100
89.1
88.7
77
N.A.
91.8
91.4
N.A.
68.2
91
88.8
87.5
N.A.
74.3
76.5
76.1
74.1
P-Site Identity:
100
0
0
0
N.A.
93.3
93.3
N.A.
93.3
86.6
93.3
86.6
N.A.
33.3
46.6
53.3
53.3
P-Site Similarity:
100
26.6
26.6
6.6
N.A.
100
100
N.A.
100
86.6
100
86.6
N.A.
73.3
80
73.3
73.3
Percent
Protein Identity:
N.A.
50.2
N.A.
52.8
N.A.
45.7
Protein Similarity:
N.A.
60.8
N.A.
63.6
N.A.
60.8
P-Site Identity:
N.A.
53.3
N.A.
40
N.A.
46.6
P-Site Similarity:
N.A.
66.6
N.A.
53.3
N.A.
80
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
65
0
0
6
0
0
12
12
0
6
6
0
0
0
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
12
0
65
0
0
0
0
24
6
0
0
0
0
% D
% Glu:
6
0
24
6
0
0
0
0
0
48
18
0
0
42
6
% E
% Phe:
12
0
0
0
0
71
0
0
53
0
0
48
0
0
0
% F
% Gly:
0
0
0
0
0
0
77
6
0
0
24
0
6
12
6
% G
% His:
0
0
0
0
6
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
83
0
0
0
0
0
0
6
0
0
0
0
0
0
% I
% Lys:
6
12
59
30
0
0
6
0
0
0
36
0
59
36
59
% K
% Leu:
0
6
0
0
12
0
0
0
18
0
0
18
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
18
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
6
0
0
0
6
0
0
0
0
12
0
0
18
0
6
% Q
% Arg:
0
0
0
42
0
0
0
0
0
0
0
0
6
0
6
% R
% Ser:
0
0
0
12
0
6
0
83
12
0
0
6
0
6
12
% S
% Thr:
0
0
6
6
6
12
0
0
0
0
0
0
0
0
0
% T
% Val:
6
0
0
0
6
0
6
0
6
12
0
12
12
0
0
% V
% Trp:
0
0
0
0
0
12
0
0
0
0
0
0
0
6
0
% W
% Tyr:
0
0
0
0
0
0
0
0
6
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _