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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SOD2
All Species:
40.3
Human Site:
S139
Identified Species:
55.42
UniProt:
P04179
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P04179
NP_000627.2
222
24722
S139
K
E
K
L
T
A
A
S
V
G
V
Q
G
S
G
Chimpanzee
Pan troglodytes
Q8HXP7
198
22186
L126
Q
G
S
G
W
G
W
L
G
F
N
K
E
R
G
Rhesus Macaque
Macaca mulatta
Q8HXP2
198
22191
L126
Q
G
S
G
W
G
W
L
G
F
N
K
E
R
G
Dog
Lupus familis
XP_862558
183
20786
N114
G
W
G
W
L
G
F
N
K
E
Q
G
R
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
P09671
222
24584
S139
K
E
K
L
T
A
V
S
V
G
V
Q
G
S
G
Rat
Rattus norvegicus
P07895
222
24656
S139
K
E
K
L
T
A
V
S
V
G
V
Q
G
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519389
312
34579
S229
K
E
K
L
T
A
V
S
V
G
V
Q
G
S
G
Chicken
Gallus gallus
NP_989542
224
24928
S141
K
E
K
L
T
A
V
S
V
G
V
Q
G
S
G
Frog
Xenopus laevis
NP_001083968
224
25147
S141
K
E
K
L
N
T
V
S
V
G
V
Q
G
S
G
Zebra Danio
Brachydanio rerio
NP_956270
224
24990
T141
K
E
K
I
S
A
A
T
V
A
V
Q
G
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q00637
217
24666
T131
K
K
E
L
T
T
L
T
V
A
V
Q
G
S
G
Honey Bee
Apis mellifera
NP_001171519
218
24507
T134
K
K
R
L
S
E
N
T
I
A
I
Q
G
S
G
Nematode Worm
Caenorhab. elegans
P31161
221
24518
T138
Q
K
Q
L
S
A
S
T
V
A
V
Q
G
S
G
Sea Urchin
Strong. purpuratus
XP_785278
224
24586
T140
R
S
K
L
S
A
A
T
V
A
I
Q
G
S
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P09233
235
25527
G151
V
K
K
M
N
A
E
G
A
A
L
Q
G
S
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O81235
231
25425
G147
V
K
K
M
S
A
E
G
A
A
V
Q
G
S
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q9Y783
245
27001
L152
K
K
A
F
S
A
A
L
L
G
I
Q
G
S
G
Conservation
Percent
Protein Identity:
100
89.1
88.2
76.1
N.A.
89.6
88.2
N.A.
63.1
83.9
81.2
80.3
N.A.
58.5
62.6
64.4
61.1
Protein Similarity:
100
89.1
88.7
77
N.A.
91.8
91.4
N.A.
68.2
91
88.8
87.5
N.A.
74.3
76.5
76.1
74.1
P-Site Identity:
100
6.6
6.6
0
N.A.
93.3
93.3
N.A.
93.3
93.3
80
73.3
N.A.
60
40
53.3
60
P-Site Similarity:
100
20
20
6.6
N.A.
93.3
93.3
N.A.
93.3
93.3
80
93.3
N.A.
80
80
93.3
86.6
Percent
Protein Identity:
N.A.
50.2
N.A.
52.8
N.A.
45.7
Protein Similarity:
N.A.
60.8
N.A.
63.6
N.A.
60.8
P-Site Identity:
N.A.
40
N.A.
46.6
N.A.
53.3
P-Site Similarity:
N.A.
60
N.A.
66.6
N.A.
80
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
6
0
0
65
24
0
12
42
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
42
6
0
0
6
12
0
0
6
0
0
12
0
0
% E
% Phe:
0
0
0
6
0
0
6
0
0
12
0
0
0
0
0
% F
% Gly:
6
12
6
12
0
18
0
12
12
42
0
6
83
0
95
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
6
0
0
0
0
6
0
18
0
0
0
0
% I
% Lys:
59
36
59
0
0
0
0
0
6
0
0
12
0
0
0
% K
% Leu:
0
0
0
59
6
0
6
18
6
0
6
0
0
6
0
% L
% Met:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
12
0
6
6
0
0
12
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
18
0
6
0
0
0
0
0
0
0
6
83
0
0
6
% Q
% Arg:
6
0
6
0
0
0
0
0
0
0
0
0
6
12
0
% R
% Ser:
0
6
12
0
36
0
6
36
0
0
0
0
0
83
0
% S
% Thr:
0
0
0
0
36
12
0
30
0
0
0
0
0
0
0
% T
% Val:
12
0
0
0
0
0
30
0
59
0
59
0
0
0
0
% V
% Trp:
0
6
0
6
12
0
12
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _