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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SOD2 All Species: 14.85
Human Site: S22 Identified Species: 20.42
UniProt: P04179 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P04179 NP_000627.2 222 24722 S22 P A L G Y L G S R Q K H S L P
Chimpanzee Pan troglodytes Q8HXP7 198 22186 I22 E P H I N A Q I M Q L H H S K
Rhesus Macaque Macaca mulatta Q8HXP2 198 22191 I22 E P H I N A Q I M Q L H H S K
Dog Lupus familis XP_862558 183 20786 S10 S R A A L S T S R T L V P A L
Cat Felis silvestris
Mouse Mus musculus P09671 222 24584 S22 P V A G A A G S R H K H S L P
Rat Rattus norvegicus P07895 222 24656 S22 P A A S T A G S R H K H S L P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519389 312 34579 S112 P A L G C L G S R Q K H T L P
Chicken Gallus gallus NP_989542 224 24928 A24 A P W G C L V A R Q K H T L P
Frog Xenopus laevis NP_001083968 224 25147 C24 P A L A Y S F C K E K H T L P
Zebra Danio Brachydanio rerio NP_956270 224 24990 S24 P L L G A V T S R Q K H A L P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q00637 217 24666 P22 V R G K H T L P K L P Y D Y A
Honey Bee Apis mellifera NP_001171519 218 24507 T23 T F T R T K H T L P D L P Y D
Nematode Worm Caenorhab. elegans P31161 221 24518 V22 P I T G V A A V R S K H S L P
Sea Urchin Strong. purpuratus XP_785278 224 24586 V23 Q A R V V S G V S S L H T L P
Poplar Tree Populus trichocarpa
Maize Zea mays P09233 235 25527 G31 A A A A S A R G V T T V T L P
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O81235 231 25425 G27 S R L L R I R G I Q T F T L P
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q9Y783 245 27001 G30 G N A T T M A G L A T Y S L P
Conservation
Percent
Protein Identity: 100 89.1 88.2 76.1 N.A. 89.6 88.2 N.A. 63.1 83.9 81.2 80.3 N.A. 58.5 62.6 64.4 61.1
Protein Similarity: 100 89.1 88.7 77 N.A. 91.8 91.4 N.A. 68.2 91 88.8 87.5 N.A. 74.3 76.5 76.1 74.1
P-Site Identity: 100 13.3 13.3 13.3 N.A. 66.6 66.6 N.A. 86.6 53.3 53.3 66.6 N.A. 0 0 53.3 33.3
P-Site Similarity: 100 13.3 13.3 13.3 N.A. 66.6 66.6 N.A. 93.3 66.6 73.3 80 N.A. 20 6.6 53.3 40
Percent
Protein Identity: N.A. 50.2 N.A. 52.8 N.A. 45.7
Protein Similarity: N.A. 60.8 N.A. 63.6 N.A. 60.8
P-Site Identity: N.A. 20 N.A. 26.6 N.A. 20
P-Site Similarity: N.A. 26.6 N.A. 40 N.A. 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 36 30 18 12 36 12 6 0 6 0 0 6 6 6 % A
% Cys: 0 0 0 0 12 0 0 6 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 6 0 6 0 6 % D
% Glu: 12 0 0 0 0 0 0 0 0 6 0 0 0 0 0 % E
% Phe: 0 6 0 0 0 0 6 0 0 0 0 6 0 0 0 % F
% Gly: 6 0 6 36 0 0 30 18 0 0 0 0 0 0 0 % G
% His: 0 0 12 0 6 0 6 0 0 12 0 65 12 0 0 % H
% Ile: 0 6 0 12 0 6 0 12 6 0 0 0 0 0 0 % I
% Lys: 0 0 0 6 0 6 0 0 12 0 48 0 0 0 12 % K
% Leu: 0 6 30 6 6 18 6 0 12 6 24 6 0 71 6 % L
% Met: 0 0 0 0 0 6 0 0 12 0 0 0 0 0 0 % M
% Asn: 0 6 0 0 12 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 42 18 0 0 0 0 0 6 0 6 6 0 12 0 71 % P
% Gln: 6 0 0 0 0 0 12 0 0 42 0 0 0 0 0 % Q
% Arg: 0 18 6 6 6 0 12 0 48 0 0 0 0 0 0 % R
% Ser: 12 0 0 6 6 18 0 36 6 12 0 0 30 12 0 % S
% Thr: 6 0 12 6 18 6 12 6 0 12 18 0 36 0 0 % T
% Val: 6 6 0 6 12 6 6 12 6 0 0 12 0 0 0 % V
% Trp: 0 0 6 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 12 0 0 0 0 0 0 12 0 12 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _