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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SOD2 All Species: 63.94
Human Site: Y200 Identified Species: 87.92
UniProt: P04179 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P04179 NP_000627.2 222 24722 Y200 Y K N V R P D Y L K A I W N V
Chimpanzee Pan troglodytes Q8HXP7 198 22186 Y176 Y K N V R P D Y L K A I W N V
Rhesus Macaque Macaca mulatta Q8HXP2 198 22191 Y176 Y K N V R P D Y L K A I W N V
Dog Lupus familis XP_862558 183 20786 L162 K N V R P D Y L K A I W N V I
Cat Felis silvestris
Mouse Mus musculus P09671 222 24584 Y200 Y K N V R P D Y L K A I W N V
Rat Rattus norvegicus P07895 222 24656 Y200 Y K N V R P D Y L K A I W N V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519389 312 34579 Y290 Y K N V R P D Y L K A I W N V
Chicken Gallus gallus NP_989542 224 24928 Y202 Y K N V R P D Y L K A I W N V
Frog Xenopus laevis NP_001083968 224 25147 Y202 Y K N V R P D Y L K A I W N V
Zebra Danio Brachydanio rerio NP_956270 224 24990 Y202 Y K N V R P D Y V K A I W N V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q00637 217 24666 Y192 Y K N V R P S Y V E A I W D I
Honey Bee Apis mellifera NP_001171519 218 24507 Y195 Y K N V R P D Y V K A I F D V
Nematode Worm Caenorhab. elegans P31161 221 24518 Y199 Y K N V R P D Y V N A I W K I
Sea Urchin Strong. purpuratus XP_785278 224 24586 Y201 Y K N V R P D Y V K A I F N I
Poplar Tree Populus trichocarpa
Maize Zea mays P09233 235 25527 Y213 Y K N V R P D Y L N N I W K V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O81235 231 25425 Y209 Y K N V R P E Y L K N V W K V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q9Y783 245 27001 Y213 Y L N G K A A Y V E N I W K V
Conservation
Percent
Protein Identity: 100 89.1 88.2 76.1 N.A. 89.6 88.2 N.A. 63.1 83.9 81.2 80.3 N.A. 58.5 62.6 64.4 61.1
Protein Similarity: 100 89.1 88.7 77 N.A. 91.8 91.4 N.A. 68.2 91 88.8 87.5 N.A. 74.3 76.5 76.1 74.1
P-Site Identity: 100 100 100 0 N.A. 100 100 N.A. 100 100 100 93.3 N.A. 66.6 80 73.3 80
P-Site Similarity: 100 100 100 6.6 N.A. 100 100 N.A. 100 100 100 100 N.A. 93.3 100 86.6 100
Percent
Protein Identity: N.A. 50.2 N.A. 52.8 N.A. 45.7
Protein Similarity: N.A. 60.8 N.A. 63.6 N.A. 60.8
P-Site Identity: N.A. 80 N.A. 73.3 N.A. 40
P-Site Similarity: N.A. 80 N.A. 86.6 N.A. 60
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 6 6 0 0 6 77 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 6 77 0 0 0 0 0 0 12 0 % D
% Glu: 0 0 0 0 0 0 6 0 0 12 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % F
% Gly: 0 0 0 6 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 6 89 0 0 24 % I
% Lys: 6 89 0 0 6 0 0 0 6 71 0 0 0 24 0 % K
% Leu: 0 6 0 0 0 0 0 6 59 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 6 95 0 0 0 0 0 0 12 18 0 6 59 0 % N
% Pro: 0 0 0 0 6 89 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 6 89 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 6 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 6 89 0 0 0 0 36 0 0 6 0 6 77 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 6 83 0 0 % W
% Tyr: 95 0 0 0 0 0 6 95 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _