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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SOD2 All Species: 46.67
Human Site: Y33 Identified Species: 64.17
UniProt: P04179 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P04179 NP_000627.2 222 24722 Y33 H S L P D L P Y D Y G A L E P
Chimpanzee Pan troglodytes Q8HXP7 198 22186 A33 H H S K H H A A Y V N N L N V
Rhesus Macaque Macaca mulatta Q8HXP2 198 22191 A33 H H S K H H A A Y V N N L N V
Dog Lupus familis XP_862558 183 20786 G21 V P A L G C L G S R Q K H S L
Cat Felis silvestris
Mouse Mus musculus P09671 222 24584 Y33 H S L P D L P Y D Y G A L E P
Rat Rattus norvegicus P07895 222 24656 Y33 H S L P D L P Y D Y G A L E P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519389 312 34579 Y123 H T L P D L P Y D Y G A L E P
Chicken Gallus gallus NP_989542 224 24928 Y35 H T L P D L P Y D Y G A L E P
Frog Xenopus laevis NP_001083968 224 25147 Y35 H T L P D L P Y D Y G A L Q P
Zebra Danio Brachydanio rerio NP_956270 224 24990 Y35 H A L P D L T Y D Y G A L E P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q00637 217 24666 P33 Y D Y A A L E P I I C R E I M
Honey Bee Apis mellifera NP_001171519 218 24507 L34 L P Y D Y K A L E P I I S A E
Nematode Worm Caenorhab. elegans P31161 221 24518 Y33 H S L P D L P Y D Y A D L E P
Sea Urchin Strong. purpuratus XP_785278 224 24586 Y34 H T L P E L P Y D Y N A L S P
Poplar Tree Populus trichocarpa
Maize Zea mays P09233 235 25527 Y42 V T L P D L S Y D F G A L E P
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O81235 231 25425 Y38 F T L P D L P Y D Y G A L E P
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q9Y783 245 27001 Y41 Y S L P Q L P Y A Y N A L E P
Conservation
Percent
Protein Identity: 100 89.1 88.2 76.1 N.A. 89.6 88.2 N.A. 63.1 83.9 81.2 80.3 N.A. 58.5 62.6 64.4 61.1
Protein Similarity: 100 89.1 88.7 77 N.A. 91.8 91.4 N.A. 68.2 91 88.8 87.5 N.A. 74.3 76.5 76.1 74.1
P-Site Identity: 100 13.3 13.3 0 N.A. 100 100 N.A. 93.3 93.3 86.6 86.6 N.A. 6.6 0 86.6 73.3
P-Site Similarity: 100 13.3 13.3 0 N.A. 100 100 N.A. 100 100 100 93.3 N.A. 13.3 6.6 86.6 86.6
Percent
Protein Identity: N.A. 50.2 N.A. 52.8 N.A. 45.7
Protein Similarity: N.A. 60.8 N.A. 63.6 N.A. 60.8
P-Site Identity: N.A. 73.3 N.A. 86.6 N.A. 73.3
P-Site Similarity: N.A. 86.6 N.A. 93.3 N.A. 80
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 6 6 6 6 0 18 12 6 0 6 65 0 6 0 % A
% Cys: 0 0 0 0 0 6 0 0 0 0 6 0 0 0 0 % C
% Asp: 0 6 0 6 59 0 0 0 65 0 0 6 0 0 0 % D
% Glu: 0 0 0 0 6 0 6 0 6 0 0 0 6 59 6 % E
% Phe: 6 0 0 0 0 0 0 0 0 6 0 0 0 0 0 % F
% Gly: 0 0 0 0 6 0 0 6 0 0 53 0 0 0 0 % G
% His: 65 12 0 0 12 12 0 0 0 0 0 0 6 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 6 6 6 6 0 6 0 % I
% Lys: 0 0 0 12 0 6 0 0 0 0 0 6 0 0 0 % K
% Leu: 6 0 71 6 0 77 6 6 0 0 0 0 83 0 6 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 24 12 0 12 0 % N
% Pro: 0 12 0 71 0 0 59 6 0 6 0 0 0 0 71 % P
% Gln: 0 0 0 0 6 0 0 0 0 0 6 0 0 6 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 6 0 6 0 0 0 % R
% Ser: 0 30 12 0 0 0 6 0 6 0 0 0 6 12 0 % S
% Thr: 0 36 0 0 0 0 6 0 0 0 0 0 0 0 0 % T
% Val: 12 0 0 0 0 0 0 0 0 12 0 0 0 0 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 12 0 12 0 6 0 0 71 12 65 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _