Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SOD2 All Species: 42.12
Human Site: Y35 Identified Species: 57.92
UniProt: P04179 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P04179 NP_000627.2 222 24722 Y35 L P D L P Y D Y G A L E P H I
Chimpanzee Pan troglodytes Q8HXP7 198 22186 V35 S K H H A A Y V N N L N V T E
Rhesus Macaque Macaca mulatta Q8HXP2 198 22191 V35 S K H H A A Y V N N L N V T E
Dog Lupus familis XP_862558 183 20786 R23 A L G C L G S R Q K H S L P D
Cat Felis silvestris
Mouse Mus musculus P09671 222 24584 Y35 L P D L P Y D Y G A L E P H I
Rat Rattus norvegicus P07895 222 24656 Y35 L P D L P Y D Y G A L E P H I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519389 312 34579 Y125 L P D L P Y D Y G A L E P H I
Chicken Gallus gallus NP_989542 224 24928 Y37 L P D L P Y D Y G A L E P H I
Frog Xenopus laevis NP_001083968 224 25147 Y37 L P D L P Y D Y G A L Q P H I
Zebra Danio Brachydanio rerio NP_956270 224 24990 Y37 L P D L T Y D Y G A L E P H I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q00637 217 24666 I35 Y A A L E P I I C R E I M E L
Honey Bee Apis mellifera NP_001171519 218 24507 P36 Y D Y K A L E P I I S A E I M
Nematode Worm Caenorhab. elegans P31161 221 24518 Y35 L P D L P Y D Y A D L E P V I
Sea Urchin Strong. purpuratus XP_785278 224 24586 Y36 L P E L P Y D Y N A L S P V I
Poplar Tree Populus trichocarpa
Maize Zea mays P09233 235 25527 F44 L P D L S Y D F G A L E P A I
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O81235 231 25425 Y40 L P D L P Y D Y G A L E P A I
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q9Y783 245 27001 Y43 L P Q L P Y A Y N A L E P Y I
Conservation
Percent
Protein Identity: 100 89.1 88.2 76.1 N.A. 89.6 88.2 N.A. 63.1 83.9 81.2 80.3 N.A. 58.5 62.6 64.4 61.1
Protein Similarity: 100 89.1 88.7 77 N.A. 91.8 91.4 N.A. 68.2 91 88.8 87.5 N.A. 74.3 76.5 76.1 74.1
P-Site Identity: 100 6.6 6.6 0 N.A. 100 100 N.A. 100 100 93.3 93.3 N.A. 6.6 0 80 73.3
P-Site Similarity: 100 6.6 6.6 0 N.A. 100 100 N.A. 100 100 100 93.3 N.A. 13.3 13.3 80 80
Percent
Protein Identity: N.A. 50.2 N.A. 52.8 N.A. 45.7
Protein Similarity: N.A. 60.8 N.A. 63.6 N.A. 60.8
P-Site Identity: N.A. 80 N.A. 93.3 N.A. 73.3
P-Site Similarity: N.A. 86.6 N.A. 93.3 N.A. 80
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 6 6 0 18 12 6 0 6 65 0 6 0 12 0 % A
% Cys: 0 0 0 6 0 0 0 0 6 0 0 0 0 0 0 % C
% Asp: 0 6 59 0 0 0 65 0 0 6 0 0 0 0 6 % D
% Glu: 0 0 6 0 6 0 6 0 0 0 6 59 6 6 12 % E
% Phe: 0 0 0 0 0 0 0 6 0 0 0 0 0 0 0 % F
% Gly: 0 0 6 0 0 6 0 0 53 0 0 0 0 0 0 % G
% His: 0 0 12 12 0 0 0 0 0 0 6 0 0 42 0 % H
% Ile: 0 0 0 0 0 0 6 6 6 6 0 6 0 6 71 % I
% Lys: 0 12 0 6 0 0 0 0 0 6 0 0 0 0 0 % K
% Leu: 71 6 0 77 6 6 0 0 0 0 83 0 6 0 6 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 6 0 6 % M
% Asn: 0 0 0 0 0 0 0 0 24 12 0 12 0 0 0 % N
% Pro: 0 71 0 0 59 6 0 6 0 0 0 0 71 6 0 % P
% Gln: 0 0 6 0 0 0 0 0 6 0 0 6 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 6 0 6 0 0 0 0 0 % R
% Ser: 12 0 0 0 6 0 6 0 0 0 6 12 0 0 0 % S
% Thr: 0 0 0 0 6 0 0 0 0 0 0 0 0 12 0 % T
% Val: 0 0 0 0 0 0 0 12 0 0 0 0 12 12 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 12 0 6 0 0 71 12 65 0 0 0 0 0 6 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _