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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: OAT All Species: 36.36
Human Site: Y245 Identified Species: 80
UniProt: P04181 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P04181 NP_000265.1 439 48535 Y245 V V V P D P G Y L M G V R E L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001082811 439 48442 Y245 V V V P D P G Y L M G V R E L
Dog Lupus familis XP_535050 440 48423 Y246 V V V P D P G Y L M G V R E L
Cat Felis silvestris
Mouse Mus musculus P29758 439 48336 Y245 V I V P D P G Y L T G V R E L
Rat Rattus norvegicus P04182 439 48314 Y245 V I V P D P G Y L T G V R E L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001006567 439 48324 Y245 V I V P D K G Y L T G V R D L
Frog Xenopus laevis NP_001165664 439 48049 Y245 V I V P D E G Y L T G V R Q L
Zebra Danio Brachydanio rerio XP_701334 444 48690 Y250 V V V P D A G Y L Q K V R E L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VW26 431 47293 Y239 V V V P S D G Y L K K V R E L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q18040 422 46435 Y226 V V L P D P G Y L K G V S D L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P07991 424 46067 P225 V P P A D Y F P K V S A L C R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 97.4 92.5 N.A. 90.8 90.6 N.A. N.A. 85.4 80.4 75.4 N.A. 70.1 N.A. 62.6 N.A.
Protein Similarity: 100 N.A. 99 97.5 N.A. 96.1 95.6 N.A. N.A. 94 90.6 88.5 N.A. 84 N.A. 78.8 N.A.
P-Site Identity: 100 N.A. 100 100 N.A. 86.6 86.6 N.A. N.A. 73.3 73.3 80 N.A. 73.3 N.A. 73.3 N.A.
P-Site Similarity: 100 N.A. 100 100 N.A. 93.3 93.3 N.A. N.A. 86.6 86.6 80 N.A. 73.3 N.A. 86.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 52.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 64 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 10 0 0 0 0 0 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % C
% Asp: 0 0 0 0 91 10 0 0 0 0 0 0 0 19 0 % D
% Glu: 0 0 0 0 0 10 0 0 0 0 0 0 0 64 0 % E
% Phe: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 91 0 0 0 73 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 37 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 10 0 0 10 19 19 0 0 0 0 % K
% Leu: 0 0 10 0 0 0 0 0 91 0 0 0 10 0 91 % L
% Met: 0 0 0 0 0 0 0 0 0 28 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 10 10 91 0 55 0 10 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 10 0 0 0 10 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 82 0 10 % R
% Ser: 0 0 0 0 10 0 0 0 0 0 10 0 10 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 37 0 0 0 0 0 % T
% Val: 100 55 82 0 0 0 0 0 0 10 0 91 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 0 91 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _