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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
All Species:
5.76
Human Site:
S257
Identified Species:
18.1
UniProt:
P04220
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P04220
XP_002348298
391
43057
S257
S
P
L
K
Q
T
I
S
R
P
K
G
V
A
L
Chimpanzee
Pan troglodytes
XP_522970
288
32022
E156
A
K
T
K
P
R
E
E
Q
Y
N
S
T
F
R
Rhesus Macaque
Macaca mulatta
XP_001116723
398
43362
R263
S
P
E
D
V
L
V
R
W
L
K
G
T
E
Q
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P01872
454
49953
S320
S
P
Q
K
K
F
I
S
K
P
N
E
V
H
K
Rat
Rattus norvegicus
P20759
326
35927
N194
I
L
H
Q
D
W
L
N
G
R
T
F
R
C
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507959
649
72041
T465
S
P
I
I
K
T
V
T
K
L
P
G
K
R
L
Chicken
Gallus gallus
P01875
446
48155
R312
F
P
M
E
E
K
M
R
K
T
K
A
S
N
A
Frog
Xenopus laevis
NP_001079873
614
68235
L454
A
S
M
K
E
V
F
L
F
K
E
K
G
E
Y
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
24.8
30.1
N.A.
N.A.
55.9
27.6
N.A.
23.2
28.2
24.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
39.6
44.9
N.A.
N.A.
66.3
41.1
N.A.
36.8
46.8
43.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
26.6
N.A.
N.A.
46.6
0
N.A.
33.3
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
33.3
N.A.
N.A.
60
20
N.A.
66.6
46.6
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
0
0
0
0
0
0
0
0
0
0
13
0
13
13
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% C
% Asp:
0
0
0
13
13
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
13
13
25
0
13
13
0
0
13
13
0
25
0
% E
% Phe:
13
0
0
0
0
13
13
0
13
0
0
13
0
13
0
% F
% Gly:
0
0
0
0
0
0
0
0
13
0
0
38
13
0
0
% G
% His:
0
0
13
0
0
0
0
0
0
0
0
0
0
13
0
% H
% Ile:
13
0
13
13
0
0
25
0
0
0
0
0
0
0
0
% I
% Lys:
0
13
0
50
25
13
0
0
38
13
38
13
13
0
25
% K
% Leu:
0
13
13
0
0
13
13
13
0
25
0
0
0
0
25
% L
% Met:
0
0
25
0
0
0
13
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
13
0
0
25
0
0
13
0
% N
% Pro:
0
63
0
0
13
0
0
0
0
25
13
0
0
0
0
% P
% Gln:
0
0
13
13
13
0
0
0
13
0
0
0
0
0
13
% Q
% Arg:
0
0
0
0
0
13
0
25
13
13
0
0
13
13
13
% R
% Ser:
50
13
0
0
0
0
0
25
0
0
0
13
13
0
0
% S
% Thr:
0
0
13
0
0
25
0
13
0
13
13
0
25
0
0
% T
% Val:
0
0
0
0
13
13
25
0
0
0
0
0
25
0
0
% V
% Trp:
0
0
0
0
0
13
0
0
13
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
13
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _