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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HLA-DRB1
All Species:
12.73
Human Site:
Y249
Identified Species:
56
UniProt:
P04229
Number Species:
5
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P04229
NP_002115
266
29914
Y249
L
G
A
G
L
F
I
Y
F
R
N
Q
K
G
H
Chimpanzee
Pan troglodytes
P18467
273
30903
Q246
L
L
V
G
I
V
I
Q
L
R
A
Q
K
G
Y
Rhesus Macaque
Macaca mulatta
NP_001037726
266
29891
Y249
L
G
A
G
L
F
I
Y
F
R
N
Q
K
G
H
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P18468
264
30213
Y247
L
R
A
G
L
F
I
Y
F
R
N
Q
K
G
Q
Rat
Rattus norvegicus
P18211
264
29858
Y247
L
G
A
G
L
F
V
Y
F
R
N
Q
K
G
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P23068
231
26259
L215
A
L
G
I
F
F
F
L
C
S
K
K
G
Q
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
54.2
92.4
N.A.
N.A.
74.4
72.5
N.A.
N.A.
43.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
68.8
95.1
N.A.
N.A.
86.8
83.4
N.A.
N.A.
58.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
46.6
100
N.A.
N.A.
86.6
86.6
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
60
100
N.A.
N.A.
86.6
93.3
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
67
0
0
0
0
0
0
0
17
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
17
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
17
84
17
0
67
0
0
0
0
0
0
% F
% Gly:
0
50
17
84
0
0
0
0
0
0
0
0
17
84
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
34
% H
% Ile:
0
0
0
17
17
0
67
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
17
17
84
0
0
% K
% Leu:
84
34
0
0
67
0
0
17
17
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
67
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% P
% Gln:
0
0
0
0
0
0
0
17
0
0
0
84
0
17
34
% Q
% Arg:
0
17
0
0
0
0
0
0
0
84
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
17
0
0
17
17
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
67
0
0
0
0
0
0
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _