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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CD74
All Species:
5.76
Human Site:
T132
Identified Species:
14.07
UniProt:
P04233
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P04233
NP_001020329.1
296
33516
T132
Q
G
P
M
Q
N
A
T
K
Y
G
N
M
T
E
Chimpanzee
Pan troglodytes
XP_001166356
296
33511
T132
Q
G
P
M
Q
N
A
T
K
Y
G
N
M
T
E
Rhesus Macaque
Macaca mulatta
XP_001099491
288
32677
Q127
M
G
A
Q
G
P
M
Q
N
A
T
K
Y
G
N
Dog
Lupus familis
XP_536468
272
30775
T112
Q
S
L
P
Q
G
P
T
Q
N
A
T
E
Y
G
Cat
Felis silvestris
Mouse
Mus musculus
P04441
279
31539
Y117
P
V
K
N
V
T
K
Y
G
N
M
T
Q
D
H
Rat
Rattus norvegicus
P10247
280
31624
Y118
P
V
K
N
V
T
K
Y
G
N
M
T
Q
D
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510042
590
63211
A318
E
P
N
C
R
D
R
A
R
L
G
S
R
A
D
Chicken
Gallus gallus
NP_001001613
286
31734
K120
D
M
P
M
E
A
M
K
P
R
S
N
K
T
E
Frog
Xenopus laevis
NP_001083266
293
33035
A122
M
N
D
L
E
Q
T
A
Q
T
N
N
K
V
E
Zebra Danio
Brachydanio rerio
NP_571665
237
26213
E77
G
Q
E
K
L
K
A
E
L
T
R
K
M
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
86.8
76.3
N.A.
72.6
73.3
N.A.
22
42.9
31.7
29
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
90.1
85.1
N.A.
84.8
82.7
N.A.
33
59.7
52.7
45.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
20
N.A.
0
0
N.A.
6.6
33.3
13.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
6.6
26.6
N.A.
0
0
N.A.
46.6
40
33.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
10
30
20
0
10
10
0
0
10
10
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
10
0
0
10
0
0
0
0
0
0
0
20
10
% D
% Glu:
10
0
10
0
20
0
0
10
0
0
0
0
10
0
40
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
30
0
0
10
10
0
0
20
0
30
0
0
10
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
20
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
20
10
0
10
20
10
20
0
0
20
20
0
0
% K
% Leu:
0
0
10
10
10
0
0
0
10
10
0
0
0
0
0
% L
% Met:
20
10
0
30
0
0
20
0
0
0
20
0
30
0
0
% M
% Asn:
0
10
10
20
0
20
0
0
10
30
10
40
0
0
10
% N
% Pro:
20
10
30
10
0
10
10
0
10
0
0
0
0
0
0
% P
% Gln:
30
10
0
10
30
10
0
10
20
0
0
0
20
0
0
% Q
% Arg:
0
0
0
0
10
0
10
0
10
10
10
0
10
0
0
% R
% Ser:
0
10
0
0
0
0
0
0
0
0
10
10
0
10
0
% S
% Thr:
0
0
0
0
0
20
10
30
0
20
10
30
0
30
0
% T
% Val:
0
20
0
0
20
0
0
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
20
0
20
0
0
10
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _