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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KRT6B All Species: 23.03
Human Site: T553 Identified Species: 72.38
UniProt: P04259 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P04259 NP_005546.2 564 60067 T553 S S T I K Y T T T S S S S R K
Chimpanzee Pan troglodytes A5A6M8 592 62520 S581 S S S V K F V S T T S S S R K
Rhesus Macaque Macaca mulatta XP_001095535 564 59948 T553 S S T I K Y T T T S S S S R K
Dog Lupus familis XP_850008 570 60565 T559 S S T I K Y T T T S S S S R K
Cat Felis silvestris
Mouse Mus musculus Q9Z331 562 60304 T550 S S S T I K Y T T S A S S S R
Rat Rattus norvegicus Q4FZU2 552 59231 T542 S S T I K Y T T T S S T R K S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514567 567 60534 T557 S S V R F S T T T S S S R K S
Chicken Gallus gallus O93532 492 53785 V481 G S T K S Y T V T T T S S T R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 76.6 98.4 88.5 N.A. 85.1 82.6 N.A. 80.4 64.5 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 82.7 99.2 92.4 N.A. 91.1 88.3 N.A. 85.3 74.2 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 60 100 100 N.A. 46.6 73.3 N.A. 53.3 46.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 93.3 100 100 N.A. 66.6 86.6 N.A. 60 66.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 13 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 13 13 0 0 0 0 0 0 0 0 0 % F
% Gly: 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 50 13 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 13 63 13 0 0 0 0 0 0 0 25 50 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 13 0 0 0 0 0 0 0 0 25 50 25 % R
% Ser: 88 100 25 0 13 13 0 13 0 75 75 88 75 13 25 % S
% Thr: 0 0 63 13 0 0 75 75 100 25 13 13 0 13 0 % T
% Val: 0 0 13 13 0 0 13 13 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 63 13 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _