KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KRT1
All Species:
4.24
Human Site:
Y465
Identified Species:
13.33
UniProt:
P04264
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P04264
NP_006112.3
644
66039
Y465
L
A
R
L
L
R
D
Y
Q
E
L
M
N
T
K
Chimpanzee
Pan troglodytes
A5A6M6
637
65471
R458
E
D
L
A
R
L
L
R
D
Y
Q
E
L
M
N
Rhesus Macaque
Macaca mulatta
XP_001098082
625
64353
Q446
N
D
L
E
D
A
L
Q
Q
A
K
E
D
L
A
Dog
Lupus familis
XP_543641
535
57544
D357
K
H
G
D
N
L
R
D
T
K
N
E
I
A
E
Cat
Felis silvestris
Mouse
Mus musculus
P04104
637
65587
L459
L
N
E
I
E
D
A
L
S
Q
C
K
E
D
L
Rat
Rattus norvegicus
Q6IMF3
625
64812
I446
A
Q
N
K
L
N
E
I
E
D
A
L
T
Q
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521385
725
77472
Y435
L
A
R
L
L
R
D
Y
Q
E
L
M
S
V
K
Chicken
Gallus gallus
O93532
492
53785
V314
S
K
F
E
A
L
Q
V
T
A
G
K
H
G
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
95.3
54.8
N.A.
76.5
78.2
N.A.
48.8
46.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.2
96.1
66.1
N.A.
85.2
86.6
N.A.
63.4
61.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
6.6
0
N.A.
6.6
6.6
N.A.
86.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
0
13.3
13.3
N.A.
20
33.3
N.A.
93.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
25
0
13
13
13
13
0
0
25
13
0
0
13
25
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% C
% Asp:
0
25
0
13
13
13
25
13
13
13
0
0
13
13
13
% D
% Glu:
13
0
13
25
13
0
13
0
13
25
0
38
13
0
13
% E
% Phe:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
13
0
0
0
0
0
0
0
13
0
0
13
0
% G
% His:
0
13
0
0
0
0
0
0
0
0
0
0
13
0
0
% H
% Ile:
0
0
0
13
0
0
0
13
0
0
0
0
13
0
0
% I
% Lys:
13
13
0
13
0
0
0
0
0
13
13
25
0
0
25
% K
% Leu:
38
0
25
25
38
38
25
13
0
0
25
13
13
13
13
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
25
0
13
0
% M
% Asn:
13
13
13
0
13
13
0
0
0
0
13
0
13
0
13
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
13
0
0
0
0
13
13
38
13
13
0
0
13
0
% Q
% Arg:
0
0
25
0
13
25
13
13
0
0
0
0
0
0
0
% R
% Ser:
13
0
0
0
0
0
0
0
13
0
0
0
13
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
25
0
0
0
13
13
0
% T
% Val:
0
0
0
0
0
0
0
13
0
0
0
0
0
13
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
25
0
13
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _