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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GAPDH All Species: 20
Human Site: S284 Identified Species: 48.89
UniProt: P04406 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P04406 NP_002037.2 335 36053 S284 T E H Q V V S S D F N S D T H
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001105471 335 35964 S284 T E H Q V V S S D F N S D T H
Dog Lupus familis XP_853318 333 36026 C282 T E D Q V V S C D F N S D T H
Cat Felis silvestris
Mouse Mus musculus P16858 333 35791 C282 T E D Q V V S C D F N S N S H
Rat Rattus norvegicus P04797 333 35809 C282 T E D Q V V S C D F N S N S H
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P00356 333 35685 C282 T E D Q V V S C D F N G D S H
Frog Xenopus laevis P51469 333 35679 T282 T Q D Q V V S T D F N G D T H
Zebra Danio Brachydanio rerio Q5XJ10 333 35766 T282 T E H Q V V S T D F N G D C R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P07487 332 35351 T281 T D E E V V S T D F L S D T H
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P17329 341 36437 T290 T E D Q V V S T D F V S D T N
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99 91.3 N.A. 93.7 93.7 N.A. N.A. 91.6 85 85.9 N.A. 75.5 N.A. 75 N.A.
Protein Similarity: 100 N.A. 99.6 92.5 N.A. 97 97 N.A. N.A. 94.6 92.5 93.1 N.A. 86.2 N.A. 86.8 N.A.
P-Site Identity: 100 N.A. 100 86.6 N.A. 73.3 73.3 N.A. N.A. 73.3 73.3 73.3 N.A. 66.6 N.A. 73.3 N.A.
P-Site Similarity: 100 N.A. 100 86.6 N.A. 86.6 86.6 N.A. N.A. 80 86.6 80 N.A. 86.6 N.A. 86.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 40 0 0 0 0 0 10 0 % C
% Asp: 0 10 60 0 0 0 0 0 100 0 0 0 80 0 0 % D
% Glu: 0 80 10 10 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 30 0 0 0 % G
% His: 0 0 30 0 0 0 0 0 0 0 0 0 0 0 80 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 80 0 20 0 10 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 10 0 90 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % R
% Ser: 0 0 0 0 0 0 100 20 0 0 0 70 0 30 0 % S
% Thr: 100 0 0 0 0 0 0 40 0 0 0 0 0 60 0 % T
% Val: 0 0 0 0 100 100 0 0 0 0 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _