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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ASL
All Species:
23.64
Human Site:
S133
Identified Species:
47.27
UniProt:
P04424
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P04424
NP_000039.2
464
51658
S133
R
Q
T
C
S
T
L
S
G
L
L
W
E
L
I
Chimpanzee
Pan troglodytes
XP_519125
616
66967
S285
R
Q
T
C
S
T
L
S
G
L
L
W
E
L
I
Rhesus Macaque
Macaca mulatta
XP_001087106
489
54426
S163
R
Q
T
C
S
T
L
S
G
L
L
W
E
L
I
Dog
Lupus familis
XP_536832
464
51774
S133
R
Q
D
C
S
R
L
S
A
L
L
W
E
L
I
Cat
Felis silvestris
Mouse
Mus musculus
Q91YI0
464
51721
S133
R
Q
T
C
S
K
L
S
A
L
L
R
V
L
I
Rat
Rattus norvegicus
P20673
461
51531
S133
R
Q
T
Y
S
K
L
S
T
F
L
K
V
L
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P05083
466
51025
S133
K
S
S
I
S
V
I
S
T
H
L
L
Q
L
I
Frog
Xenopus laevis
NP_001087626
443
49451
R122
D
Q
V
V
T
D
M
R
L
W
L
R
D
S
C
Zebra Danio
Brachydanio rerio
XP_002666083
465
52089
K134
R
D
G
I
A
T
L
K
E
L
A
L
Q
L
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624062
461
52688
L133
R
K
A
I
D
V
L
L
K
K
L
M
K
F
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780183
575
64473
Y246
R
D
S
L
E
C
M
Y
P
M
V
K
N
L
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P04076
463
51971
L134
R
D
I
V
N
D
T
L
F
P
A
L
K
G
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
75
84.8
93.5
N.A.
93.9
89
N.A.
N.A.
69.5
69.1
70.5
N.A.
N.A.
52.1
N.A.
52.7
Protein Similarity:
100
75
87.9
96.5
N.A.
95.6
91.8
N.A.
N.A.
85.4
82.5
84.9
N.A.
N.A.
70.4
N.A.
64.3
P-Site Identity:
100
100
100
80
N.A.
73.3
60
N.A.
N.A.
33.3
13.3
40
N.A.
N.A.
26.6
N.A.
20
P-Site Similarity:
100
100
100
80
N.A.
73.3
60
N.A.
N.A.
60
33.3
53.3
N.A.
N.A.
40
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
54.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
72.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
9
0
0
0
17
0
17
0
0
0
0
% A
% Cys:
0
0
0
42
0
9
0
0
0
0
0
0
0
0
9
% C
% Asp:
9
25
9
0
9
17
0
0
0
0
0
0
9
0
0
% D
% Glu:
0
0
0
0
9
0
0
0
9
0
0
0
34
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
9
9
0
0
0
9
0
% F
% Gly:
0
0
9
0
0
0
0
0
25
0
0
0
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
0
0
9
25
0
0
9
0
0
0
0
0
0
0
84
% I
% Lys:
9
9
0
0
0
17
0
9
9
9
0
17
17
0
0
% K
% Leu:
0
0
0
9
0
0
67
17
9
50
75
25
0
75
9
% L
% Met:
0
0
0
0
0
0
17
0
0
9
0
9
0
0
0
% M
% Asn:
0
0
0
0
9
0
0
0
0
0
0
0
9
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
9
9
0
0
0
0
0
% P
% Gln:
0
59
0
0
0
0
0
0
0
0
0
0
17
0
0
% Q
% Arg:
84
0
0
0
0
9
0
9
0
0
0
17
0
0
0
% R
% Ser:
0
9
17
0
59
0
0
59
0
0
0
0
0
9
0
% S
% Thr:
0
0
42
0
9
34
9
0
17
0
0
0
0
0
0
% T
% Val:
0
0
9
17
0
17
0
0
0
0
9
0
17
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
9
0
34
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _