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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 13.33
Human Site: Y108 Identified Species: 73.33
UniProt: P04432 Number Species: 4
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P04432 XP_002346449 129 14235 Y108 Q P E D F A T Y Y C Q Q N Y N
Chimpanzee Pan troglodytes XP_001141313 236 25781 Y108 Q P D D F A T Y Y C Q Q F G S
Rhesus Macaque Macaca mulatta XP_001110149 133 14498 Y108 Q P E D F A T Y Y C Q Q H N K
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P01637 128 14367 Y106 E Y E D M G I Y Y C L Q Y D E
Rat Rattus norvegicus XP_002729495 253 27856 Y106 E P E D F A V Y Y C Q Q G I L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 42.3 69.9 N.A. N.A. 58.9 32.4 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 48.3 78.9 N.A. N.A. 77.5 41.5 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 73.3 80 N.A. N.A. 40 66.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 86.6 86.6 N.A. N.A. 46.6 73.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 80 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 % C
% Asp: 0 0 20 100 0 0 0 0 0 0 0 0 0 20 0 % D
% Glu: 40 0 80 0 0 0 0 0 0 0 0 0 0 0 20 % E
% Phe: 0 0 0 0 80 0 0 0 0 0 0 0 20 0 0 % F
% Gly: 0 0 0 0 0 20 0 0 0 0 0 0 20 20 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 20 0 0 % H
% Ile: 0 0 0 0 0 0 20 0 0 0 0 0 0 20 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 20 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 20 0 0 0 20 % L
% Met: 0 0 0 0 20 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 20 20 20 % N
% Pro: 0 80 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 60 0 0 0 0 0 0 0 0 0 80 100 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 20 % S
% Thr: 0 0 0 0 0 0 60 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 20 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 20 0 0 0 0 0 100 100 0 0 0 20 20 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _