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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 16.67
Human Site: Y108 Identified Species: 73.33
UniProt: P04434 Number Species: 5
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P04434 XP_001719147 116 12757 Y108 P E D F A V Y Y C Q Q D H N L
Chimpanzee Pan troglodytes XP_001150960 133 14526 Y109 P D D F A T Y Y C Q Q Y S S T
Rhesus Macaque Macaca mulatta XP_001089800 235 25361 Y107 P E D F A A Y Y C L Q D G T S
Dog Lupus familis XP_854722 117 12765 Y107 P E D V A V Y Y C Q Q Y N S G
Cat Felis silvestris
Mouse Mus musculus P01633 149 16415 Y128 A E D L A V Y Y C Q Q H Y S T
Rat Rattus norvegicus XP_002726184 159 17234 Y113 A E D L A V Y Y C E Q Y Y S Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 60.9 44.6 75.2 N.A. 46.3 47.7 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 70.6 45.9 84.6 N.A. 59.7 60.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 60 66.6 66.6 N.A. 60 53.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 73.3 66.6 80 N.A. 73.3 73.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 34 0 0 0 100 17 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 % C
% Asp: 0 17 100 0 0 0 0 0 0 0 0 34 0 0 0 % D
% Glu: 0 84 0 0 0 0 0 0 0 17 0 0 0 0 0 % E
% Phe: 0 0 0 50 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 17 0 17 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 17 17 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 34 0 0 0 0 0 17 0 0 0 0 17 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 17 17 0 % N
% Pro: 67 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 67 100 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 17 67 17 % S
% Thr: 0 0 0 0 0 17 0 0 0 0 0 0 0 17 34 % T
% Val: 0 0 0 17 0 67 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 100 100 0 0 0 50 34 0 17 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _