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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WNT1
All Species:
25.76
Human Site:
S142
Identified Species:
47.22
UniProt:
P04628
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P04628
NP_005421.1
370
40982
S142
V
T
H
S
V
A
R
S
C
S
E
G
S
I
E
Chimpanzee
Pan troglodytes
XP_523686
423
47308
S198
V
A
F
A
V
T
R
S
C
A
E
G
T
S
T
Rhesus Macaque
Macaca mulatta
XP_001105191
370
40978
S142
V
T
H
S
V
A
R
S
C
S
E
G
S
I
E
Dog
Lupus familis
XP_543686
611
66494
S383
V
T
H
S
V
A
R
S
C
S
E
G
S
I
E
Cat
Felis silvestris
Mouse
Mus musculus
P04426
370
41067
S142
V
T
H
S
V
A
R
S
C
S
E
G
S
I
E
Rat
Rattus norvegicus
Q9QXQ5
351
39025
G131
V
T
R
A
C
S
S
G
D
L
E
K
C
G
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Q07DZ8
361
40096
G131
I
T
R
A
C
S
Q
G
E
L
K
S
C
S
C
Chicken
Gallus gallus
Q2LMP1
352
39611
I135
C
A
E
G
S
A
T
I
C
G
C
D
T
R
H
Frog
Xenopus laevis
P10108
371
41107
S142
V
T
H
S
V
A
R
S
C
S
E
G
S
I
E
Zebra Danio
Brachydanio rerio
P24257
370
40992
S141
V
T
H
A
V
A
R
S
C
S
E
G
A
I
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P09615
468
51968
A145
V
T
H
S
I
A
R
A
C
S
E
G
T
I
E
Honey Bee
Apis mellifera
XP_396946
412
46385
A158
V
T
H
S
I
A
R
A
C
S
E
G
S
I
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P28094
223
25218
K10
E
S
C
T
C
D
Y
K
F
R
G
D
S
G
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.4
99.7
60.3
N.A.
98.9
44.3
N.A.
43.2
42.1
69.8
75.9
N.A.
44.4
53.4
N.A.
38.1
Protein Similarity:
100
55
99.7
60.3
N.A.
99.1
58.6
N.A.
60.8
58.6
83.8
88.6
N.A.
55.7
65
N.A.
44.8
P-Site Identity:
100
46.6
100
100
N.A.
100
20
N.A.
6.6
13.3
100
86.6
N.A.
80
80
N.A.
6.6
P-Site Similarity:
100
66.6
100
100
N.A.
100
33.3
N.A.
40
20
100
100
N.A.
100
100
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
0
31
0
70
0
16
0
8
0
0
8
0
0
% A
% Cys:
8
0
8
0
24
0
0
0
77
0
8
0
16
0
16
% C
% Asp:
0
0
0
0
0
8
0
0
8
0
0
16
0
0
0
% D
% Glu:
8
0
8
0
0
0
0
0
8
0
77
0
0
0
54
% E
% Phe:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
0
16
0
8
8
70
0
16
0
% G
% His:
0
0
62
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
8
0
0
0
16
0
0
8
0
0
0
0
0
62
0
% I
% Lys:
0
0
0
0
0
0
0
8
0
0
8
8
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
16
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% Q
% Arg:
0
0
16
0
0
0
70
0
0
8
0
0
0
8
0
% R
% Ser:
0
8
0
54
8
16
8
54
0
62
0
8
54
16
0
% S
% Thr:
0
77
0
8
0
8
8
0
0
0
0
0
24
0
8
% T
% Val:
77
0
0
0
54
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _