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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WNT1
All Species:
25.15
Human Site:
S212
Identified Species:
46.11
UniProt:
P04628
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P04628
NP_005421.1
370
40982
S212
A
G
R
T
T
V
F
S
E
M
R
Q
E
C
K
Chimpanzee
Pan troglodytes
XP_523686
423
47308
D268
A
G
R
T
T
I
L
D
H
M
H
L
K
C
K
Rhesus Macaque
Macaca mulatta
XP_001105191
370
40978
S212
A
G
R
T
T
V
F
S
E
M
R
Q
E
C
K
Dog
Lupus familis
XP_543686
611
66494
S453
A
G
R
T
T
V
F
S
E
M
R
Q
E
C
K
Cat
Felis silvestris
Mouse
Mus musculus
P04426
370
41067
S212
A
G
R
T
T
V
F
S
E
M
R
Q
E
C
K
Rat
Rattus norvegicus
Q9QXQ5
351
39025
R195
L
H
N
N
E
A
G
R
K
A
I
L
T
H
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Q07DZ8
361
40096
A194
M
N
L
H
N
N
R
A
G
R
K
A
V
K
R
Chicken
Gallus gallus
Q2LMP1
352
39611
E197
A
G
R
T
S
I
I
E
L
M
H
L
K
C
K
Frog
Xenopus laevis
P10108
371
41107
T212
A
G
R
L
T
V
L
T
E
M
R
Q
E
C
K
Zebra Danio
Brachydanio rerio
P24257
370
40992
S211
A
G
R
M
T
V
A
S
E
M
Q
Q
E
C
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P09615
468
51968
A227
A
G
R
A
H
V
Q
A
E
M
R
Q
E
C
K
Honey Bee
Apis mellifera
XP_396946
412
46385
S231
A
G
R
A
H
V
S
S
E
M
R
Q
E
C
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P28094
223
25218
C72
S
S
E
M
R
R
E
C
K
C
H
G
M
S
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.4
99.7
60.3
N.A.
98.9
44.3
N.A.
43.2
42.1
69.8
75.9
N.A.
44.4
53.4
N.A.
38.1
Protein Similarity:
100
55
99.7
60.3
N.A.
99.1
58.6
N.A.
60.8
58.6
83.8
88.6
N.A.
55.7
65
N.A.
44.8
P-Site Identity:
100
53.3
100
100
N.A.
100
0
N.A.
0
46.6
80
80
N.A.
73.3
80
N.A.
0
P-Site Similarity:
100
66.6
100
100
N.A.
100
6.6
N.A.
20
66.6
86.6
86.6
N.A.
80
80
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
77
0
0
16
0
8
8
16
0
8
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
8
0
0
0
77
0
% C
% Asp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% D
% Glu:
0
0
8
0
8
0
8
8
62
0
0
0
62
0
0
% E
% Phe:
0
0
0
0
0
0
31
0
0
0
0
0
0
0
0
% F
% Gly:
0
77
0
0
0
0
8
0
8
0
0
8
0
0
8
% G
% His:
0
8
0
8
16
0
0
0
8
0
24
0
0
8
0
% H
% Ile:
0
0
0
0
0
16
8
0
0
0
8
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
16
0
8
0
16
8
77
% K
% Leu:
8
0
8
8
0
0
16
0
8
0
0
24
0
0
0
% L
% Met:
8
0
0
16
0
0
0
0
0
77
0
0
8
0
8
% M
% Asn:
0
8
8
8
8
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
8
0
0
0
8
62
0
0
0
% Q
% Arg:
0
0
77
0
8
8
8
8
0
8
54
0
0
0
8
% R
% Ser:
8
8
0
0
8
0
8
47
0
0
0
0
0
8
0
% S
% Thr:
0
0
0
47
54
0
0
8
0
0
0
0
8
0
0
% T
% Val:
0
0
0
0
0
62
0
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _