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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WNT1
All Species:
19.09
Human Site:
S263
Identified Species:
35
UniProt:
P04628
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P04628
NP_005421.1
370
40982
S263
V
L
Y
G
N
R
G
S
N
R
A
S
R
A
E
Chimpanzee
Pan troglodytes
XP_523686
423
47308
E319
M
V
V
E
K
H
R
E
S
R
G
W
V
E
T
Rhesus Macaque
Macaca mulatta
XP_001105191
370
40978
S263
V
L
Y
G
N
R
G
S
N
R
A
S
R
A
E
Dog
Lupus familis
XP_543686
611
66494
S504
V
L
Y
G
N
R
G
S
N
R
A
S
R
A
E
Cat
Felis silvestris
Mouse
Mus musculus
P04426
370
41067
S263
V
L
Y
G
N
R
G
S
N
R
A
S
R
A
E
Rat
Rattus norvegicus
Q9QXQ5
351
39025
E245
F
D
G
A
T
E
V
E
P
R
R
V
G
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Q07DZ8
361
40096
Q244
R
K
Y
N
G
A
I
Q
V
V
M
N
Q
D
G
Chicken
Gallus gallus
Q2LMP1
352
39611
E248
M
V
V
E
K
H
R
E
S
R
G
W
V
E
T
Frog
Xenopus laevis
P10108
371
41107
S263
V
T
Y
S
N
N
G
S
N
R
W
G
S
R
S
Zebra Danio
Brachydanio rerio
P24257
370
40992
S262
V
V
Y
A
N
K
G
S
N
R
A
S
H
R
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P09615
468
51968
R278
V
Q
V
T
N
S
L
R
A
T
N
A
L
A
P
Honey Bee
Apis mellifera
XP_396946
412
46385
R282
V
M
V
S
N
S
D
R
V
R
G
N
G
N
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P28094
223
25218
E122
D
G
S
P
S
D
R
E
T
E
S
S
F
V
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.4
99.7
60.3
N.A.
98.9
44.3
N.A.
43.2
42.1
69.8
75.9
N.A.
44.4
53.4
N.A.
38.1
Protein Similarity:
100
55
99.7
60.3
N.A.
99.1
58.6
N.A.
60.8
58.6
83.8
88.6
N.A.
55.7
65
N.A.
44.8
P-Site Identity:
100
6.6
100
100
N.A.
100
6.6
N.A.
6.6
6.6
46.6
60
N.A.
20
20
N.A.
6.6
P-Site Similarity:
100
26.6
100
100
N.A.
100
13.3
N.A.
20
26.6
46.6
73.3
N.A.
26.6
33.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
16
0
8
0
0
8
0
39
8
0
39
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
0
0
8
8
0
0
0
0
0
0
8
0
% D
% Glu:
0
0
0
16
0
8
0
31
0
8
0
0
0
16
31
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
8
8
31
8
0
47
0
0
0
24
8
16
0
8
% G
% His:
0
0
0
0
0
16
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
0
16
8
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
31
0
0
0
0
8
0
0
0
0
0
8
0
0
% L
% Met:
16
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
8
62
8
0
0
47
0
8
16
0
8
0
% N
% Pro:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
16
% P
% Gln:
0
8
0
0
0
0
0
8
0
0
0
0
8
0
0
% Q
% Arg:
8
0
0
0
0
31
24
16
0
77
8
0
31
16
0
% R
% Ser:
0
0
8
16
8
16
0
47
16
0
8
47
8
8
16
% S
% Thr:
0
8
0
8
8
0
0
0
8
8
0
0
0
0
16
% T
% Val:
62
24
31
0
0
0
8
0
16
8
0
8
16
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
16
0
0
0
% W
% Tyr:
0
0
54
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _