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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WNT1
All Species:
19.7
Human Site:
S81
Identified Species:
36.11
UniProt:
P04628
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P04628
NP_005421.1
370
40982
S81
Q
N
P
G
I
L
H
S
V
S
G
G
L
Q
S
Chimpanzee
Pan troglodytes
XP_523686
423
47308
S136
N
Y
I
E
I
M
P
S
V
A
E
G
V
K
L
Rhesus Macaque
Macaca mulatta
XP_001105191
370
40978
S81
Q
N
P
G
I
L
H
S
V
S
G
G
L
Q
S
Dog
Lupus familis
XP_543686
611
66494
S322
Q
N
P
G
I
L
H
S
V
S
G
G
L
Q
S
Cat
Felis silvestris
Mouse
Mus musculus
P04426
370
41067
S81
Q
N
P
G
I
L
H
S
V
S
G
G
L
Q
S
Rat
Rattus norvegicus
Q9QXQ5
351
39025
I75
R
H
G
A
Q
L
A
I
E
E
C
Q
Y
Q
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Q07DZ8
361
40096
E76
G
I
A
E
W
T
A
E
C
Q
H
Q
F
R
Q
Chicken
Gallus gallus
Q2LMP1
352
39611
Q80
G
I
Q
E
C
Q
H
Q
F
R
G
R
R
W
N
Frog
Xenopus laevis
P10108
371
41107
S81
Q
N
P
G
I
L
Q
S
I
T
R
G
L
H
S
Zebra Danio
Brachydanio rerio
P24257
370
40992
A80
Q
N
P
G
I
L
H
A
I
A
A
G
L
H
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P09615
468
51968
A81
D
N
P
G
V
L
G
A
L
V
K
G
A
N
L
Honey Bee
Apis mellifera
XP_396946
412
46385
A94
E
N
P
G
V
L
M
A
V
A
R
G
A
N
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P28094
223
25218
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.4
99.7
60.3
N.A.
98.9
44.3
N.A.
43.2
42.1
69.8
75.9
N.A.
44.4
53.4
N.A.
38.1
Protein Similarity:
100
55
99.7
60.3
N.A.
99.1
58.6
N.A.
60.8
58.6
83.8
88.6
N.A.
55.7
65
N.A.
44.8
P-Site Identity:
100
26.6
100
100
N.A.
100
13.3
N.A.
0
13.3
66.6
60
N.A.
33.3
40
N.A.
0
P-Site Similarity:
100
53.3
100
100
N.A.
100
26.6
N.A.
6.6
20
80
86.6
N.A.
53.3
66.6
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
0
0
16
24
0
24
8
0
16
0
0
% A
% Cys:
0
0
0
0
8
0
0
0
8
0
8
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
0
0
24
0
0
0
8
8
8
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
8
% F
% Gly:
16
0
8
62
0
0
8
0
0
0
39
70
0
0
0
% G
% His:
0
8
0
0
0
0
47
0
0
0
8
0
0
16
0
% H
% Ile:
0
16
8
0
54
0
0
8
16
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% K
% Leu:
0
0
0
0
0
70
0
0
8
0
0
0
47
0
16
% L
% Met:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% M
% Asn:
8
62
0
0
0
0
0
0
0
0
0
0
0
16
8
% N
% Pro:
0
0
62
0
0
0
8
0
0
0
0
0
0
0
0
% P
% Gln:
47
0
8
0
8
8
8
8
0
8
0
16
0
39
16
% Q
% Arg:
8
0
0
0
0
0
0
0
0
8
16
8
8
8
0
% R
% Ser:
0
0
0
0
0
0
0
47
0
31
0
0
0
0
39
% S
% Thr:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
8
% T
% Val:
0
0
0
0
16
0
0
0
47
8
0
0
8
0
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _