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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WNT1
All Species:
41.82
Human Site:
Y291
Identified Species:
76.67
UniProt:
P04628
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P04628
NP_005421.1
370
40982
Y291
P
S
P
H
D
L
V
Y
F
E
K
S
P
N
F
Chimpanzee
Pan troglodytes
XP_523686
423
47308
Y344
P
T
E
R
D
L
V
Y
Y
E
N
S
P
N
F
Rhesus Macaque
Macaca mulatta
XP_001105191
370
40978
Y291
P
S
P
H
D
L
V
Y
F
E
K
S
P
N
F
Dog
Lupus familis
XP_543686
611
66494
Y532
P
S
P
H
D
L
V
Y
F
E
K
S
P
N
F
Cat
Felis silvestris
Mouse
Mus musculus
P04426
370
41067
Y291
P
S
P
H
D
L
V
Y
F
E
K
S
P
N
F
Rat
Rattus norvegicus
Q9QXQ5
351
39025
Y272
H
T
D
E
D
L
V
Y
L
E
P
S
P
D
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Q07DZ8
361
40096
Y271
P
T
K
N
D
L
V
Y
F
E
N
S
P
D
Y
Chicken
Gallus gallus
Q2LMP1
352
39611
Y273
P
T
E
K
D
L
V
Y
Y
E
N
S
P
N
F
Frog
Xenopus laevis
P10108
371
41107
Y292
P
S
S
Q
D
L
V
Y
F
E
K
S
P
N
F
Zebra Danio
Brachydanio rerio
P24257
370
40992
Y291
P
S
S
R
D
L
V
Y
F
E
K
S
P
N
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P09615
468
51968
Y389
P
G
S
K
D
L
V
Y
L
E
P
S
P
S
F
Honey Bee
Apis mellifera
XP_396946
412
46385
Y333
P
G
P
K
D
L
V
Y
L
E
P
S
P
P
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P28094
223
25218
N147
R
D
L
V
Y
F
E
N
S
P
D
F
C
E
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.4
99.7
60.3
N.A.
98.9
44.3
N.A.
43.2
42.1
69.8
75.9
N.A.
44.4
53.4
N.A.
38.1
Protein Similarity:
100
55
99.7
60.3
N.A.
99.1
58.6
N.A.
60.8
58.6
83.8
88.6
N.A.
55.7
65
N.A.
44.8
P-Site Identity:
100
66.6
100
100
N.A.
100
53.3
N.A.
60
66.6
86.6
86.6
N.A.
60
66.6
N.A.
0
P-Site Similarity:
100
80
100
100
N.A.
100
66.6
N.A.
86.6
80
86.6
86.6
N.A.
66.6
66.6
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
8
8
0
93
0
0
0
0
0
8
0
0
16
0
% D
% Glu:
0
0
16
8
0
0
8
0
0
93
0
0
0
8
0
% E
% Phe:
0
0
0
0
0
8
0
0
54
0
0
8
0
0
85
% F
% Gly:
0
16
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
8
0
0
31
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
8
24
0
0
0
0
0
0
47
0
0
0
0
% K
% Leu:
0
0
8
0
0
93
0
0
24
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
8
0
0
24
0
0
62
0
% N
% Pro:
85
0
39
0
0
0
0
0
0
8
24
0
93
8
0
% P
% Gln:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
0
0
16
0
0
0
0
0
0
0
0
0
0
8
% R
% Ser:
0
47
24
0
0
0
0
0
8
0
0
93
0
8
0
% S
% Thr:
0
31
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
8
0
0
93
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
93
16
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _