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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TP53
All Species:
16.67
Human Site:
S378
Identified Species:
45.83
UniProt:
P04637
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P04637
NP_000537.3
393
43653
S378
S
K
K
G
Q
S
T
S
R
H
K
K
L
M
F
Chimpanzee
Pan troglodytes
XP_511957
405
44926
S390
S
K
K
G
Q
S
T
S
R
H
K
K
L
M
F
Rhesus Macaque
Macaca mulatta
P56424
393
43637
S378
S
K
K
G
Q
S
T
S
R
H
K
K
F
M
F
Dog
Lupus familis
XP_861368
586
65737
A502
I
P
E
Q
F
R
H
A
I
W
K
G
I
L
D
Cat
Felis silvestris
Mouse
Mus musculus
P02340
387
43137
S372
T
K
K
G
Q
S
T
S
R
H
K
K
T
M
V
Rat
Rattus norvegicus
P10361
391
43433
S376
T
K
K
G
Q
S
T
S
R
H
K
K
P
M
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P10360
367
40151
V350
S
K
G
R
R
V
K
V
E
G
P
Q
P
S
C
Frog
Xenopus laevis
P07193
363
40674
K348
C
R
D
E
I
K
P
K
K
G
K
K
L
L
V
Zebra Danio
Brachydanio rerio
P79734
373
41881
K357
N
R
E
S
S
E
P
K
Q
G
K
K
L
M
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97
95.6
29.1
N.A.
77.6
77.8
N.A.
N.A.
54.2
51.4
51.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
97
97.1
44
N.A.
83.2
83.9
N.A.
N.A.
67.1
65.3
63.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
6.6
N.A.
80
80
N.A.
N.A.
13.3
20
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
33.3
N.A.
86.6
86.6
N.A.
N.A.
26.6
40
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% A
% Cys:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% C
% Asp:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
12
% D
% Glu:
0
0
23
12
0
12
0
0
12
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
12
0
0
0
0
0
0
0
12
0
34
% F
% Gly:
0
0
12
56
0
0
0
0
0
34
0
12
0
0
0
% G
% His:
0
0
0
0
0
0
12
0
0
56
0
0
0
0
0
% H
% Ile:
12
0
0
0
12
0
0
0
12
0
0
0
12
0
12
% I
% Lys:
0
67
56
0
0
12
12
23
12
0
89
78
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
45
23
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
67
0
% M
% Asn:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
12
0
0
0
0
23
0
0
0
12
0
23
0
0
% P
% Gln:
0
0
0
12
56
0
0
0
12
0
0
12
0
0
0
% Q
% Arg:
0
23
0
12
12
12
0
0
56
0
0
0
0
0
0
% R
% Ser:
45
0
0
12
12
56
0
56
0
0
0
0
0
12
0
% S
% Thr:
23
0
0
0
0
0
56
0
0
0
0
0
12
0
0
% T
% Val:
0
0
0
0
0
12
0
12
0
0
0
0
0
0
34
% V
% Trp:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _