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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSPB1
All Species:
4.55
Human Site:
T174
Identified Species:
12.5
UniProt:
P04792
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P04792
NP_001531.1
205
22783
T174
A
P
M
P
K
L
A
T
Q
S
N
E
I
T
I
Chimpanzee
Pan troglodytes
XP_519162
189
20888
Q159
P
M
P
K
L
A
T
Q
S
N
E
I
T
I
P
Rhesus Macaque
Macaca mulatta
P02488
172
19774
S142
A
D
G
M
L
T
F
S
G
P
K
I
Q
T
G
Dog
Lupus familis
XP_536576
175
20048
V145
S
S
D
G
V
L
T
V
N
G
P
R
K
Q
A
Cat
Felis silvestris
Mouse
Mus musculus
P14602
209
22995
T178
A
P
L
P
K
A
V
T
Q
S
A
E
I
T
I
Rat
Rattus norvegicus
P42930
206
22874
K175
T
V
E
A
P
L
P
K
A
V
T
Q
S
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q00649
193
21653
V163
S
P
D
G
M
L
T
V
E
A
P
L
P
K
P
Frog
Xenopus laevis
NP_001087285
213
23719
I182
A
P
L
P
K
P
A
I
Q
S
A
E
I
S
I
Zebra Danio
Brachydanio rerio
NP_001008615
199
22360
V169
S
C
L
S
P
E
G
V
L
T
V
E
A
P
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.7
38
42.4
N.A.
83.7
83
N.A.
N.A.
65.8
67.1
62.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
91.7
51.7
55.6
N.A.
90.4
89.8
N.A.
N.A.
78
80.2
75.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
13.3
6.6
N.A.
73.3
6.6
N.A.
N.A.
13.3
66.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
20
13.3
N.A.
80
13.3
N.A.
N.A.
33.3
80
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
45
0
0
12
0
23
23
0
12
12
23
0
12
12
12
% A
% Cys:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
23
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
12
0
0
12
0
0
12
0
12
45
0
0
12
% E
% Phe:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
12
23
0
0
12
0
12
12
0
0
0
0
12
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
12
0
0
0
23
34
12
34
% I
% Lys:
0
0
0
12
34
0
0
12
0
0
12
0
12
12
0
% K
% Leu:
0
0
34
0
23
45
0
0
12
0
0
12
0
0
12
% L
% Met:
0
12
12
12
12
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
12
12
12
0
0
0
0
% N
% Pro:
12
45
12
34
23
12
12
0
0
12
23
0
12
12
23
% P
% Gln:
0
0
0
0
0
0
0
12
34
0
0
12
12
12
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% R
% Ser:
34
12
0
12
0
0
0
12
12
34
0
0
12
12
0
% S
% Thr:
12
0
0
0
0
12
34
23
0
12
12
0
12
34
0
% T
% Val:
0
12
0
0
12
0
12
34
0
12
12
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _