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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CYBB All Species: 28.18
Human Site: S525 Identified Species: 56.36
UniProt: P04839 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P04839 NP_000388.2 570 65336 S525 N E F K T I A S Q H P N T R I
Chimpanzee Pan troglodytes XP_001136590 570 65247 S525 N E F K T I A S Q H P N T R I
Rhesus Macaque Macaca mulatta XP_001083654 570 65303 S525 N E F K T I A S Q H P N T R I
Dog Lupus familis XP_549136 564 65065 N519 N E F S T I A N A H P R S V V
Cat Felis silvestris
Mouse Mus musculus Q61093 570 65286 S525 N E F K T I A S E H P N T T I
Rat Rattus norvegicus Q672K1 568 64398 Y523 E E F K Q I A Y N H P S S S I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514075 571 65286 S526 N E F K T I A S Q H P S S R V
Chicken Gallus gallus NP_001093756 571 65555 R526 N E F K T I A R Q H P G S R I
Frog Xenopus laevis NP_001085924 570 64842 N525 N E F K T I A N Q H Q S S R V
Zebra Danio Brachydanio rerio NP_956708 565 64471 S523 N E F S L I A S Q H P G T K V
Tiger Blowfish Takifugu rubipres NP_001027904 565 64536 S523 N E F T N I A S K H P G S K V
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O81211 948 107256 R905 E V F S S I A R K H P N S T V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.5 96.6 57.8 N.A. 93.1 57.8 N.A. 88 84.4 80 68.4 68 N.A. N.A. N.A. N.A.
Protein Similarity: 100 97.8 97.7 71.7 N.A. 96.8 72.1 N.A. 93.3 90.1 86.8 80.5 79.8 N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 53.3 N.A. 86.6 53.3 N.A. 80 80 66.6 66.6 53.3 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 73.3 N.A. 93.3 66.6 N.A. 100 86.6 93.3 80 80 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 23.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 37.9 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 40 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 66.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 100 0 9 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 17 92 0 0 0 0 0 0 9 0 0 0 0 0 0 % E
% Phe: 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 25 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 100 0 0 0 0 0 0 0 0 50 % I
% Lys: 0 0 0 67 0 0 0 0 17 0 0 0 0 17 0 % K
% Leu: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 84 0 0 0 9 0 0 17 9 0 0 42 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 92 0 0 0 0 % P
% Gln: 0 0 0 0 9 0 0 0 59 0 9 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 17 0 0 0 9 0 50 0 % R
% Ser: 0 0 0 25 9 0 0 59 0 0 0 25 59 9 0 % S
% Thr: 0 0 0 9 67 0 0 0 0 0 0 0 42 17 0 % T
% Val: 0 9 0 0 0 0 0 0 0 0 0 0 0 9 50 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _