KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPN1
All Species:
40.91
Human Site:
S222
Identified Species:
75
UniProt:
P04843
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P04843
NP_002941.1
607
68569
S222
K
V
H
Y
E
N
N
S
P
F
L
T
I
T
S
Chimpanzee
Pan troglodytes
XP_001139195
607
68657
S222
K
V
H
Y
E
N
N
S
P
F
L
T
I
T
S
Rhesus Macaque
Macaca mulatta
XP_001097494
607
68713
S222
K
V
H
Y
E
N
N
S
P
F
L
T
I
T
S
Dog
Lupus familis
XP_848830
607
68558
S222
K
V
H
Y
E
N
N
S
P
F
L
T
I
T
S
Cat
Felis silvestris
Mouse
Mus musculus
Q91YQ5
608
68510
S223
K
V
H
Y
E
N
N
S
P
F
L
T
I
T
S
Rat
Rattus norvegicus
P07153
605
68286
S220
K
V
H
Y
E
N
N
S
P
F
L
T
I
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518675
326
37335
Chicken
Gallus gallus
XP_414360
596
67229
S211
K
V
H
Y
E
N
N
S
P
F
L
T
I
T
S
Frog
Xenopus laevis
NP_001082504
595
67243
S210
K
V
H
Y
E
N
N
S
P
F
L
T
I
T
S
Zebra Danio
Brachydanio rerio
NP_922916
598
67598
S213
K
I
H
Y
E
N
N
S
P
F
L
T
I
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_995680
458
51691
D87
I
D
V
K
D
A
S
D
K
S
V
P
F
K
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782614
603
67267
S219
K
V
H
Y
E
N
N
S
P
F
L
T
V
T
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P41543
476
54053
D106
N
S
T
T
A
P
G
D
D
G
E
S
E
I
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.6
96.2
N.A.
95
94.4
N.A.
48.2
83.8
77.7
70.8
N.A.
34.9
N.A.
N.A.
52.8
Protein Similarity:
100
99.6
99
98
N.A.
98.3
98
N.A.
51.7
91
88.9
85.3
N.A.
50.9
N.A.
N.A.
71.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
100
100
86.6
N.A.
0
N.A.
N.A.
86.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
0
100
100
100
N.A.
20
N.A.
N.A.
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
8
0
0
16
8
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
77
0
0
0
0
0
8
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
77
0
0
8
0
0
% F
% Gly:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% G
% His:
0
0
77
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
0
0
0
0
0
0
0
0
0
0
70
8
0
% I
% Lys:
77
0
0
8
0
0
0
0
8
0
0
0
0
8
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
77
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
77
77
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
8
0
0
77
0
0
8
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% R
% Ser:
0
8
0
0
0
0
8
77
0
8
0
8
0
8
70
% S
% Thr:
0
0
8
8
0
0
0
0
0
0
0
77
0
70
8
% T
% Val:
0
70
8
0
0
0
0
0
0
0
8
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
77
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _