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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPN1
All Species:
39.09
Human Site:
S276
Identified Species:
71.67
UniProt:
P04843
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P04843
NP_002941.1
607
68569
S276
Q
P
D
S
G
I
S
S
I
R
S
F
K
T
I
Chimpanzee
Pan troglodytes
XP_001139195
607
68657
S276
Q
P
D
S
G
I
S
S
I
R
S
F
K
T
I
Rhesus Macaque
Macaca mulatta
XP_001097494
607
68713
S276
Q
P
D
S
G
I
S
S
I
R
S
F
K
T
I
Dog
Lupus familis
XP_848830
607
68558
S276
Q
P
D
S
G
I
A
S
I
R
S
F
K
T
I
Cat
Felis silvestris
Mouse
Mus musculus
Q91YQ5
608
68510
S277
Q
P
D
S
G
I
S
S
I
R
S
F
K
T
I
Rat
Rattus norvegicus
P07153
605
68286
S274
Q
P
D
S
G
I
S
S
I
R
S
F
K
T
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518675
326
37335
D9
I
L
P
A
A
A
Q
D
V
Y
Y
R
D
E
I
Chicken
Gallus gallus
XP_414360
596
67229
S265
Q
P
D
S
G
I
S
S
V
K
S
F
K
T
I
Frog
Xenopus laevis
NP_001082504
595
67243
S264
Q
T
D
S
G
I
S
S
V
K
S
F
K
T
I
Zebra Danio
Brachydanio rerio
NP_922916
598
67598
S267
Q
S
D
S
G
I
S
S
V
K
S
F
K
T
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_995680
458
51691
Q140
E
I
R
Q
N
D
K
Q
F
V
K
Y
T
G
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782614
603
67267
S272
R
T
Q
D
G
F
S
S
V
K
S
Y
K
T
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P41543
476
54053
E159
E
E
Q
H
L
L
W
E
T
N
R
L
P
L
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.6
96.2
N.A.
95
94.4
N.A.
48.2
83.8
77.7
70.8
N.A.
34.9
N.A.
N.A.
52.8
Protein Similarity:
100
99.6
99
98
N.A.
98.3
98
N.A.
51.7
91
88.9
85.3
N.A.
50.9
N.A.
N.A.
71.8
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
6.6
86.6
80
80
N.A.
0
N.A.
N.A.
46.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
100
93.3
93.3
N.A.
13.3
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
8
8
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
70
8
0
8
0
8
0
0
0
0
8
0
0
% D
% Glu:
16
8
0
0
0
0
0
8
0
0
0
0
0
8
0
% E
% Phe:
0
0
0
0
0
8
0
0
8
0
0
70
0
0
0
% F
% Gly:
0
0
0
0
77
0
0
0
0
0
0
0
0
8
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
0
0
0
70
0
0
47
0
0
0
0
0
85
% I
% Lys:
0
0
0
0
0
0
8
0
0
31
8
0
77
0
0
% K
% Leu:
0
8
0
0
8
8
0
0
0
0
0
8
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
8
% N
% Pro:
0
54
8
0
0
0
0
0
0
0
0
0
8
0
0
% P
% Gln:
70
0
16
8
0
0
8
8
0
0
0
0
0
0
0
% Q
% Arg:
8
0
8
0
0
0
0
0
0
47
8
8
0
0
0
% R
% Ser:
0
8
0
70
0
0
70
77
0
0
77
0
0
0
8
% S
% Thr:
0
16
0
0
0
0
0
0
8
0
0
0
8
77
0
% T
% Val:
0
0
0
0
0
0
0
0
39
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
8
16
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _