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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RPN1 All Species: 38.48
Human Site: Y161 Identified Species: 70.56
UniProt: P04843 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P04843 NP_002941.1 607 68569 Y161 V V F E G N H Y F Y S P Y P T
Chimpanzee Pan troglodytes XP_001139195 607 68657 Y161 V V F E G N H Y F Y S P Y P T
Rhesus Macaque Macaca mulatta XP_001097494 607 68713 Y161 V V F E G N H Y F Y S P Y P T
Dog Lupus familis XP_848830 607 68558 Y161 V V F E G N H Y F Y S P Y P T
Cat Felis silvestris
Mouse Mus musculus Q91YQ5 608 68510 Y162 V V F E G N H Y F Y S P Y P T
Rat Rattus norvegicus P07153 605 68286 Y159 V V F E G N H Y F Y S P Y P T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518675 326 37335
Chicken Gallus gallus XP_414360 596 67229 Y150 V V F E G N H Y F Y S P Y F T
Frog Xenopus laevis NP_001082504 595 67243 Y149 V T F E G S H Y F Y S P Y P T
Zebra Danio Brachydanio rerio NP_922916 598 67598 Y152 V V F Q G N H Y L Y S P Y P T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_995680 458 51691 L26 A L G A L L C L A T A N G E I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782614 603 67267 Y158 V E F T G N A Y F L S P Y T T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P41543 476 54053 A45 R T I D V S N A Y I S E T I E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 98.6 96.2 N.A. 95 94.4 N.A. 48.2 83.8 77.7 70.8 N.A. 34.9 N.A. N.A. 52.8
Protein Similarity: 100 99.6 99 98 N.A. 98.3 98 N.A. 51.7 91 88.9 85.3 N.A. 50.9 N.A. N.A. 71.8
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 0 93.3 86.6 86.6 N.A. 0 N.A. N.A. 66.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 0 93.3 93.3 93.3 N.A. 13.3 N.A. N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.9 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 40.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 8 0 0 8 8 8 0 8 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 8 0 62 0 0 0 0 0 0 0 8 0 8 8 % E
% Phe: 0 0 77 0 0 0 0 0 70 0 0 0 0 8 0 % F
% Gly: 0 0 8 0 77 0 0 0 0 0 0 0 8 0 0 % G
% His: 0 0 0 0 0 0 70 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 0 0 0 0 0 0 8 0 0 0 8 8 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 8 0 0 8 8 0 8 8 8 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 70 8 0 0 0 0 8 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 77 0 62 0 % P
% Gln: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 16 0 0 0 0 85 0 0 0 0 % S
% Thr: 0 16 0 8 0 0 0 0 0 8 0 0 8 8 77 % T
% Val: 77 62 0 0 8 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 77 8 70 0 0 77 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _