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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPN1
All Species:
35.76
Human Site:
Y264
Identified Species:
65.56
UniProt:
P04843
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P04843
NP_002941.1
607
68569
Y264
L
K
G
P
F
S
R
Y
D
Y
Q
R
Q
P
D
Chimpanzee
Pan troglodytes
XP_001139195
607
68657
Y264
L
K
G
P
F
S
R
Y
D
Y
Q
R
Q
P
D
Rhesus Macaque
Macaca mulatta
XP_001097494
607
68713
Y264
L
K
G
P
F
S
R
Y
D
Y
Q
R
Q
P
D
Dog
Lupus familis
XP_848830
607
68558
Y264
L
K
G
P
F
S
R
Y
D
Y
Q
R
Q
P
D
Cat
Felis silvestris
Mouse
Mus musculus
Q91YQ5
608
68510
Y265
L
K
G
P
F
S
R
Y
D
Y
Q
R
Q
P
D
Rat
Rattus norvegicus
P07153
605
68286
Y262
L
K
G
P
F
S
R
Y
D
Y
Q
R
Q
P
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518675
326
37335
Chicken
Gallus gallus
XP_414360
596
67229
Y253
L
K
G
P
F
S
R
Y
D
Y
Q
R
Q
P
D
Frog
Xenopus laevis
NP_001082504
595
67243
Y252
L
K
G
P
F
S
R
Y
D
Y
Q
R
Q
T
D
Zebra Danio
Brachydanio rerio
NP_922916
598
67598
Y255
L
K
G
P
F
S
R
Y
D
Y
Q
R
Q
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_995680
458
51691
R128
T
V
A
S
K
G
I
R
P
H
P
E
E
I
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782614
603
67267
R260
V
L
K
G
P
F
S
R
Y
D
Y
Q
R
T
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P41543
476
54053
H147
V
G
I
P
Y
P
E
H
V
G
M
S
E
E
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.6
96.2
N.A.
95
94.4
N.A.
48.2
83.8
77.7
70.8
N.A.
34.9
N.A.
N.A.
52.8
Protein Similarity:
100
99.6
99
98
N.A.
98.3
98
N.A.
51.7
91
88.9
85.3
N.A.
50.9
N.A.
N.A.
71.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
100
93.3
93.3
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
0
100
93.3
93.3
N.A.
13.3
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
70
8
0
0
0
0
70
% D
% Glu:
0
0
0
0
0
0
8
0
0
0
0
8
16
8
0
% E
% Phe:
0
0
0
0
70
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
70
8
0
8
0
0
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
8
0
0
0
0
0
0
8
0
% I
% Lys:
0
70
8
0
8
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
70
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
77
8
8
0
0
8
0
8
0
0
54
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
70
8
70
0
16
% Q
% Arg:
0
0
0
0
0
0
70
16
0
0
0
70
8
0
8
% R
% Ser:
0
0
0
8
0
70
8
0
0
0
0
8
0
8
0
% S
% Thr:
8
0
0
0
0
0
0
0
0
0
0
0
0
16
0
% T
% Val:
16
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
70
8
70
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _