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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPN2
All Species:
25.45
Human Site:
S105
Identified Species:
50.91
UniProt:
P04844
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P04844
NP_001129243.1
631
69284
S105
S
G
C
E
I
S
I
S
N
E
T
K
D
L
L
Chimpanzee
Pan troglodytes
XP_514629
576
63564
L71
L
S
G
F
G
L
P
L
A
S
Q
E
A
L
S
Rhesus Macaque
Macaca mulatta
XP_001097464
601
65921
S96
L
F
Y
A
A
Q
A
S
Q
A
L
S
G
C
E
Dog
Lupus familis
XP_865679
631
69015
S105
S
G
C
E
I
S
I
S
N
E
T
K
D
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBG6
631
69044
S105
S
G
C
E
I
S
V
S
N
E
T
K
E
L
L
Rat
Rattus norvegicus
P25235
631
69059
S105
S
G
C
E
I
S
V
S
N
E
T
R
D
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006288
631
68881
S106
S
G
C
E
V
T
I
S
N
E
T
R
E
L
L
Frog
Xenopus laevis
NP_001079661
631
69212
T105
S
S
C
E
V
T
I
T
N
E
T
R
D
L
L
Zebra Danio
Brachydanio rerio
NP_997913
630
68922
T106
E
I
L
V
S
N
D
T
R
D
L
L
L
A
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611265
634
69211
D106
L
G
C
S
A
K
I
D
E
G
L
L
S
K
V
Honey Bee
Apis mellifera
XP_395511
673
75606
S133
N
C
Q
A
N
S
L
S
N
I
I
K
I
F
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783899
827
89264
L103
L
G
N
C
K
V
P
L
S
N
G
Q
Q
V
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.5
94.1
95.8
N.A.
92.3
93.8
N.A.
N.A.
78.1
73.2
66.7
N.A.
33.7
32.6
N.A.
33.3
Protein Similarity:
100
88.9
94.6
98
N.A.
95.4
96
N.A.
N.A.
90.3
86.5
82.7
N.A.
52.2
52
N.A.
49.9
P-Site Identity:
100
6.6
6.6
100
N.A.
86.6
86.6
N.A.
N.A.
73.3
66.6
0
N.A.
20
26.6
N.A.
13.3
P-Site Similarity:
100
13.3
6.6
100
N.A.
100
100
N.A.
N.A.
100
93.3
20
N.A.
26.6
40
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
17
17
0
9
0
9
9
0
0
9
9
0
% A
% Cys:
0
9
59
9
0
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
0
0
0
0
0
0
9
9
0
9
0
0
34
0
0
% D
% Glu:
9
0
0
50
0
0
0
0
9
50
0
9
17
0
9
% E
% Phe:
0
9
0
9
0
0
0
0
0
0
0
0
0
9
0
% F
% Gly:
0
59
9
0
9
0
0
0
0
9
9
0
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
34
0
42
0
0
9
9
0
9
0
0
% I
% Lys:
0
0
0
0
9
9
0
0
0
0
0
34
0
9
0
% K
% Leu:
34
0
9
0
0
9
9
17
0
0
25
17
9
59
59
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
9
0
9
9
0
0
59
9
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
17
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
9
0
0
9
0
0
9
0
9
9
9
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
9
0
0
25
0
0
0
% R
% Ser:
50
17
0
9
9
42
0
59
9
9
0
9
9
0
9
% S
% Thr:
0
0
0
0
0
17
0
17
0
0
50
0
0
0
17
% T
% Val:
0
0
0
9
17
9
17
0
0
0
0
0
0
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _